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Although tens of millions of individuals worldwide use NSAIDs daily, balancing the competing risks and benefits of these agents continues to be a challenge. Evidence-based treatment guidelines and expert opinions have been promulgated, but will they actually translate to improved patient care? A new web-based tool could aid physicians' treatment decision-making.
Autologous bone grafts are the 'gold standard' repair strategy for large defects of bone, but a growing body of evidence suggests that synthetic biomaterials designed to have osteoinductive properties could provide an alternative approach.
The 1987 ACR classification criteria for rheumatoid arthritis were criticized for their lack of sensitivity in early disease. To overcome this limitation, new criteria have now been developed. The question is how will these criteria be implemented in clinical and basic research, and in daily clinical practice?
