Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Renal pathological changes seen in individuals with the zoonotic disease leptospirosis include interstitial nephritis and tubular necrosis. With a particular emphasis on the role of hemodynamics, this author from Thailand examines the pathogenesis of renal dysfunction in leptospirosis. The utility of dopamine in this setting is contrasted with its effects in renal dysfunction of other etiologies.