News & Comment

Repetitive sensory input induces long-term potentiation of pyramidal cell synapses in mouse somatosensory cortex by activation of higher-order thalamic projections and disinhibition of local interneurons.

In mice, long-term potentiation of hippocampal–nucleus accumbens synapses is required for the formation of reward-related memories.

A study shows that application of spatiotemporally patterned epidural electrical stimulation alongside rehabilitation allowed individuals with spinal cord injury and severe locomotor deficits to walk with limited assistance.

Meal-associated thermogenesis in brown fat is triggered by the gut hormone secretin and signals to the brain to promote satiation in mice.

Two studies show that tau pathology drives the expression of complement molecules that in turn promote the phagocytosis of synapses and neuroinflammation.

Dopamine released in the rodent prefrontal cortex increases the signal-to-noise ratio of responses to aversive stimuli that are transmitted to the periaqueductal grey.

A study shows that during brain development in mice, CD47 prevents excessive synaptic pruning by microglia.

A population of spinal excitatory interneurons can be targeted for the maintenance of respiratory function after spinal cord injury in mice.

Dendritic mitochondria in stimulated neurons undergo fission that is required for long-term potentiation.