News & Comment

Dopamine receptor subtypes 1 and 2 in the prefrontal cortex contribute to rule-based executive function via differential but complementary effects.

Obesity arising from a poor diet often leads to hypertension, and a new study shows that apdipose-derived leptin, acting on neurons in the dorsomedial hypothalams is necessary and sufficient to induce hypertension.

Neurons in cortical area MT have a crucial role in representing motion in depth.

Mouse and human fibroblasts can be reprogrammed to become peripheral sensory neuronsin vitrothrough overexpression of certain combinations of transcription factors.

Events that cause circadian arrhythmia such as travel across time zones or shift work impair memory formation and in hamsters this is shown to require intact circuitry in the suprachiasmatic nucleus.

Reduced sociability in frontotemporal dementia may be due, at least in part, to a reduction in miR-124 levels resulting in altered AMPA receptor composition and function in the frontal cortex.

The majority of neurons in the geniculate ganglion — which receives inputs from taste receptor cells on the tongue — are singly tuned to a particular taste quality.

Age-related memory impairment is thought to result from cumulative oxidative damage in neurons, but this study shows that in Drosophila melanogaster, these memory impairments are as a result of reduced D-serine production by glia.

Study usesin vivogene-specific chromatin remodelling to elucidate the role of Fosb in addiction- and depression-related changes in the brain.

Place-cell firing in mice can be accompanied by regenerative dendritic events, which predict some of the properties of place fields.