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The number of neural stem cells in the brain decreases with age, which in the dentate gyrus of older mice is associated with a lower SIRT7-mediated mitochondrial unfolded protein response and reduced neural stem cell maintenance and neurogenesis.
A brain–computer interface can decode semantic representations of perceived and imagined stimuli at the level of words and phrases from functional MRI recordings of brain activity.
Neuronal activity in the secondary motor cortex of mice engaged in a foraging task simultaneously represents multiple alternative decision-making strategies.
Oxytocin-releasing projections from the paraventricular nucleus enhance top-down nociceptive regulation in rats by altering the excitation–inhibition balance in the prefrontal cortex.
Thalamic activity onto a sparse population of premotor neurons in the zebra finch song nucleus initiates syllable onset, enabling the orchestration of song production.
Infant attachment to the mother in rodents and monkeys is shown to rely on regulation of hypothalamic oxytocin release by a serotonergic projection from the raphe nucleus.
New findings indicate a role for SMN protein in assembly of the synaptic SNARE complex at neuromuscular junctions, providing insight into mechanisms of pathology in spinal muscular atrophy.
The centrosome is crucial for the microtubule dynamics that underlie the radial migration of developing rodent neurons but is not required for axon growth.
A new study examines thalamic innervation of cortical layer 2/3 pyramidal neurons and models how this thalamic connectivity affects visual responses in these cells.
The ability to be woken from deep sleep by a sound (such as an alarm) is shown to be mediated by a specialized glutamatergic brainstem–mediodorsal thalamic pathway.
A 1997 paper, described here by Hiromasa Takemura, showed that variations in the size of the visual cortex in humans are correlated with those of other parts of the visual system.
Different defensive responses are characterized by transient behavioural and cardiac components, which are constrained by cardiovascular dynamics occurring across the duration of threat exposure.
