News & Comment

During nervous system development, secretion of netrin 1 from both the floorplate and the ventricular zone is shown to be important for guidance of commissural axons towards the ventral midline of the spinal cord.

The secreted fragment of the amyloid precursor protein binds to a subunit of GABA_B receptors to modulate neurotransmission.

In a mouse model of multiple sclerosis, calcium enters neurons via ‘nanoruptures’ in the cell membrane and accumulates in the cytoplasm of axons, driving axonal degeneration.

Sophisticated optical techniques reveal subpopulations of orbitofrontal cortex neurons that mediate interactions between social feedback and feeding.

Neurons in the mouse postrhinal cortex receive visual inputs from the superior colliculus and respond to visual motion independently of the primary visual cortex.

A mouse model reveals a central role for microglial activation and altered glial cell dynamics in the lasting neurological and cognitive dysfunction following methotrexate chemotherapy.