News & Comment

In a working memory task, the neural code for the target stimulus in the lateral prefrontal cortex transforms when a distractor is presented, without loss of target-related information.

In recent years, several funding agencies have introduced requirements for researchers to consider sex as a biological variable in preclinical research. In this Comment article, McCarthy and colleagues discuss the potential impact of these policies for neuroscience research.

Apolipoprotein E4 promotes tau neurotoxicity in a mouse model of tau-mediated neurodegenerative disease.

Surface diffusion of AMPA receptors at the postsynpatic membrane of hippocampal synapses is shown to be crucial for the expression of both short-term plasticity and early long-term potentiation.

The type 2 cytokine interleukin-4 directly stimulates and sensitizes sensory neurons to drive chronic itch.

Two pathways from CA1 to the entorhinal cortex — a direct pathway and an indirect pathway, that projects via the hippocampal subiculum — are shown to play dissociable roles in memory formation and retrieval, respectively.

In mice, the circular RNA Cdr1as regulates microRNA expression in the brain and sensorimotor gating.

A study in mice identified neurons in the central amygdala that express the serotonin 2A receptor and positively reinforce the consumption of food.

In mice, a set of projections from the medial prefrontal cortex to the nucleus accumbens suppress reward seeking under risky conditions.

The activity of neurons in the basal ganglia contributes to the weighting of speed versus accuracy, rather than to deliberation, in a motor decision-making task.