News & Comment

Endogenous β-actin mRNA is masked from translation by association with a protein complex and is released by synaptic activity.

In mice, excessive maternal calorie intake during lactation 'metabolically programmes' offspring by altering their hypothalamic axon projections.

A new study shows that responsiveness of theCaenorhabditis elegansASH avoidance circuit to aversive stimuli is reduced during sleep and reveals that re-establishment of synchrony between interneurons in this circuit is crucial for rapid reversal to wakefulness.

In mice, behavioural training is effective at attenuating old fear memories in mice if these memories are epigenetically 'primed' after recall by treatment with a histone deacetylase inhibitor.

Lateral inhibition of photoreceptors in the zebrafish retina is mediated by proton efflux from horizontal cells.

A new study reveals that epidermal cells engulf and degrade degenerating dendrites in theDrosophila melanogasterperipheral nervous system.

A new study shows that myelination may proceed in activity-dependent and -independent manners and that activity-dependent myelination is linked to neuregulin-induced signalling in oligodendrocytes, which makes these cells more sensitive to glutamate release.

The scientific and legal interest in functional MRI-based lie detection has grown rapidly in the past decade. In this Perspective, Farah and colleagues review the scientific state of the art of this approach to lie detection, discuss its legal status and consider broader ethical and societal implications.

Pregnenolone is strongly upregulated by Δ⁹-tetrahydrocannabinol (THC) and limits several addictive and other effects of THC.

Microglia promote learning-induced formation of glutamatergic synapses, and this effect is mediated by microglial brain-derived neurotrophic factor.