News & Comment

The anti-ageing factor Klotho modulates cognition independently of its effects on ageing.

Pain-sensitive sensory neurons in the dorsal root ganglion release calcitonin gene-related peptide, which could over time have long-term consequences on metabolism and longevity by reducing pancreatic release of insulin.

CB1 cannabinoid receptors at the terminals of glutamatergic corticostriatal neurons exert neuroprotective effects by preventing excitotoxicity.

A high-fat diet causes persistent changes in the structure and function of the mouse olfactory system.

Stimulation of sleepers' brains with 40 Hz currents during rapid eye movement sleep can induce lucid dreaming.

Neurogenesis — in infancy or adulthood — induces forgetting of established memories.

Dopaminergic neurons in the substantia nigra pars compacta and ventral tegmental area co-release GABA in the striatum that is not synthesizedde novobut rather is taken up by presynaptic GABA transporters.

Three studies show that exposure to young blood improves brain and muscle function in aged mice.

Synchronized, high-frequency gamma oscillations contribute to successful decision making in a working-memory task in mice and may, therefore, reflect content in working memory entering the animal's 'awareness'.

A new study shows that reducing mutant huntingtin expression in both striatal and cortical neurons is required to prevent disease pathogenesis in a mouse model of Huntington's disease.