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  • Two new studies expand the optogenetic repertoire by showing light-induced inhibition of synaptic release and control of gene transcription and chromatin modifications.

    • Leonie Welberg
    Research Highlight
  • Psychology and neuroscience studies have shown that memory is a reconstructive process that is susceptible to distortion. Lacy and Stark summarize the evidence and discuss how this insight could be applied to police and courtroom procedures.

    • Joyce W. Lacy
    • Craig E. L. Stark
    Science and Society
  • The location of glia is a key factor that determines synapse location during postembryonic growth inCaenorhabditis elegans.

    • Darran Yates
    Research Highlight
  • A new study reveals a signalling pathway that stabilizes the expression of a single olfactory receptor by an olfactory sensory neuron.

    • Katherine Whalley
    Research Highlight
  • Stopping a movement involves a race between distinct pathways through the basal ganglia that converge on the same neurons.

    • Leonie Welberg
    Research Highlight
  • Oligodendrocytes support neurons by releasing exosomes that are internalized by neurons, and the cargo that they contain is shown to provide metabolic support under conditions of cellular stress.

    • Sian Lewis
    Research Highlight
  • Cheng and Ji show that in a mouse model of Alzheimer's disease, new spatial memory formation by hippocampal place cells is disrupted by an inability to encode external environmental information and by dominating internally generated brain activity.

    • Sian Lewis
    Research Highlight
  • Attention increases synaptic efficacy and improves signal-to-noise processing at thalamocortical synapses.

    • Leonie Welberg
    Research Highlight
  • A study reveals a signalling pathway in the mouse cortex that immobilizes mitochondria at nascent presynaptic sites in developing axons and thereby promotes terminal axon branching.

    • Darran Yates
    Research Highlight
  • A new study reveals that an interaction between Ca2+/calmodulin and the vesicle-priming protein MUNC13-1 has a crucial role in replenishment of the presynaptic readily releasable pool of vesicles after depletion by high-frequency stimulation.

    • Sian Lewis
    Research Highlight