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AMP-activated protein kinase (AMPK), which is expressed in the hypothalamus and activated by fasting, is shown to increase the phosphorylation of p21-activated kinase 2 (PAK2), and induce spinogenesis and an increase in excitatory neurotransmission in hypothalamic AgRP neurons.
Developmental dysfunction in peripheral somatosensory neurons causes altered responses to tactile stimuli and other behavioural deficits in mouse models of autism spectrum disorder.
A disinhibitory circuit involving the central nucleus of the amygdala, inhibitory and excitatory neurons in the ventrolateral periaqueductal grey and premotor neurons in the medulla controls freezing behaviour in response to threat.
Although both cocaine and morphine administration induce silent synapses in dopaminergic medium spiny neurons and produce similar behavioural changes, they do so through different mechanisms and by affecting different neuronal sub-populations.
There is greater 'overlap' between the sets of CA1 neurons encoding temporally close memories than of neurons encoding memories temporally spaced apart; such overlap may enable linking of temporally close memories.