News & Comment

A system inDrosophila melanogasterthat involves Diuretic hormone 44 (a homologue of mammalian corticotropin-releasing hormone) mediates the preferential ingestion and digestion of nutritive sugars.

Sleep reduces the activity of the dopamine neurons that promote forgetting inDrosophila melanogaster.

A study shows that elevated levels of the microRNA encoded by the schizophrenia-linked genemir-137impair presynaptic plasticity and hippocampus-dependent learning and memory in mice.

Research into the underlying pathology of c9FTD/ALS has been hampered by a lack of good mouse models, but a new study reports a mouse model that recapitulates both the cellular and the behavioural pathology associated with these disorders.

Components of the RNA repair and splicing machinery are shown to have a role in regulating axon regenerative capacity in fly sensory neurons.

Interactions among semaphorin 6A, plexin A2 and plexin A4, and between contactin 4 and amyloid precursor protein, are crucial for the normal development of the circuits underlying vertical and horizontal optokinetic reflexes, respectively.

Disruption of actin polymerization in the frontal cortex, which causes abnormal dendritic spine structures, results in locomotor hyperactivity owing to dysregulation of a midbrain dopaminergic circuit.

A study uses optogenetics to dissect the circuits involved in associating environmental stimuli with positive or negative outcomes.

Reelin induces transcriptional changes in neurons by increasing the formation of an intracellular fragment of its target receptor that interacts with specific enhancer regions in the nucleus.