Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
In mice, the endocannabinoid system inhibits glutamatergic signalling from the olfactory cortex to the main olfactory bulb after fasting, increasing the detection of food odours and, consequently, enhancing food consumption.
The membrane lipid arachidonic acid is released from the postsynaptic neuron and can potentiate synaptic transmission by inhibiting presynaptic voltage-gated potassium channels.
A sufficient number of microglia must be present during postnatal development to ensure normal long-range connectivity and social behaviour in adulthood.
Fear extinction induces a shift in the balance of activity between 'fear neurons' and 'extinction neurons' in the basal amygdala, which project to prelimbic and infralimbic portions of the medial prefrontal cortex, respectively.
A new study shows that responsiveness of theCaenorhabditis elegansASH avoidance circuit to aversive stimuli is reduced during sleep and reveals that re-establishment of synchrony between interneurons in this circuit is crucial for rapid reversal to wakefulness.
In mice, behavioural training is effective at attenuating old fear memories in mice if these memories are epigenetically 'primed' after recall by treatment with a histone deacetylase inhibitor.
A new study shows that myelination may proceed in activity-dependent and -independent manners and that activity-dependent myelination is linked to neuregulin-induced signalling in oligodendrocytes, which makes these cells more sensitive to glutamate release.
