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This study identifies 1,445 RNA viruses in invertebrate animals, including new virus families, and uncovers unexpected levels of evolutionary flexibility.
This month's Genome Watch describes how whole-genome sequencing used for surveillance purposes has enabled the identification of new drug resistance markers in the malaria parasite.
Protists are an important part of the marine food web. In this Review, Caronet al. summarize recent insights from transcriptomic studies of cultured and free-living protists and discuss how these findings highlight the functions and interactions of these single-celled eukaryotes in the global oceans.
In this Review, Tsirigotakiet al. discuss recent biochemical, structural and mechanistic insights that have been gained into the consecutive steps of the general secretory (Sec) pathway. They focus on the architecture and dynamics of SecYEG and its regulation by ribosomes and SecA, and present current models of the mechanisms and energetics of the Sec-pathway-dependent secretion process in bacteria.
In this Review, De Nizet al. discuss the contribution of key imaging tools to advances in our understanding of Plasmodiumspp. biology and host–pathogen interactions over the past decade. These advances, pertaining to parasite structure and motility, as well as the liver and blood stages, have led to paradigm shifts in our knowledge of malaria.
The microbiota is central for host homeostasis and affects not only the gut but also other organs, including the lungs. In this Opinion article, Hansbro and colleagues explore the role of the microbiota in the gut–lung axis and lung disease.
