Review

Nature Reviews Molecular Cell Biology 5, 1024-1037 (December 2004) | doi:10.1038/nrm1524

Making sense of it all: bacterial chemotaxis

George H. Wadhams1 & Judith P. Armitage1  About the authors

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Bacteria must be able to respond to a changing environment, and one way to respond is to move. The transduction of sensory signals alters the concentration of small phosphorylated response regulators that bind to the rotary flagellar motor and cause switching. This simple pathway has provided a paradigm for sensory systems in general. However, the increasing number of sequenced bacterial genomes shows that although the central sensory mechanism seems to be common to all bacteria, there is added complexity in a wide range of species.

Author affiliations

  1. Department of Biochemistry, University of Oxford, Oxford OX1 3QU, UK.

Correspondence to: Judith P. Armitage1 Email: judith.armitage@bioch.ox.ac.uk

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