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  • Focus |

    Cytoskeletal elements are essential mediators of signalling and can influence many cellular processes through this capacity. Accordingly, there has been a huge drive to understand the intricacies of cytoskeletal dynamics — from what regulates cytoskeletal elements to their effects on cells — and the rapid advances being made in cell and molecular biology approaches, and, in particular, in imaging techniques, are allowing us to scrutinize these processes.

  • Focus |

    Since the early studies of the 17th century, microscopy has played a vital role in biological discovery − it enabled Robert Hooke to describe cells and Antonie van Leeuwenhoek to discover bacteria. Four centuries later, microscopy techniques remain at the centre of cell-biological research.

  • Milestone |

    Milestones in Development is a collaboration between five journals - Nature,Nature Cell Biology,Nature Reviews Genetics,Nature Reviews Molecular Cell BiologyandNature Reviews Neuroscience. Twenty-four 'Milestones' highlight the discoveries that have made the greatest impact on the developmental biology field over the past 100 years.

  • Focus |

    Nature Cell BiologyandNature Reviews Molecular Cell Biologyare pleased to present a joint supplement on imaging in cell biology. The specially commissioned articles focus on key advances in imaging techniques, which allow us to follow cell-biological events ranging from the dynamics of single molecules in living cells to the development of whole organisms.

  • Focus |

    Calcium is a crucial intracellular signal that is responsible for regulating many cellular processes, including embryonic development, cell proliferation, apoptosis, cardiac contractility, and learning and memory. This Focus brings together a selection of relevant articles from across Nature Research journals.

  • Focus |

    In this Focus, we look at several well-established signalling pathways as well as those that have recently emerged or recently been proposed. It is not surprising, therefore, that the signalling field often seems overwhelming, and our aim is to make it accessible to everyone.

  • Focus |

    In this Focus, we look at the various mechanisms behind cell death in general, and apoptosis in particular.

  • Focus |

    This Focus contains a selection of review, perspective and research highlight articles on stem cells from the Nature Reviews journals.

  • Focus |

    As the mechanisms behind processes of gene expression and chromatin remodelling are unravelled, the aim of this Focus is to provide a beginner's guide to some of the molecules involved.

  • Milestone |

    A specially written series of short articles on the main discoveries that have shaped the field of cell division.

  • Milestone |

    Milestones in Cell Division is a collaboration between four journals - Nature,Nature Cell Biology,Nature Reviews CancerandNature Reviews Molecular Cell Biology- which celebrates the past 100 years of research in the field of cell division. Twenty three 'Milestones' describe some of the seminal discoveries and place them in the context of what was known at the time.

  • Focus |

    We hope this Focus will provide both a welcome introduction to the uninitiated and a wealth of new ideas for those already familiar with the functionally diverse ubiquitin and proteasome families.