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  • Focus |

    This Collection on fluorescence imaging illustrates the versatility of fluorescence imaging technologies in studying basic cell-biological processes, disease aetiology and therapeutics.

  • Focus |

    Nature Cell BiologyandNature Reviews Molecular Cell Biologyhave joined forces to present this collection of reviews and commentaries, designed as highly accessible and practical guides to some of the most important approaches and challenges in systems biology. This user's guide also contains lists of glossary terms, further reading and systems biology research institutions, as well as a library of related articles across the Nature titles.

  • Series |

    Understanding the molecular and cellular basis of diseases is vital for dissecting the mechanisms of disease pathogenesis and for designing appropriate and effective treatments. In a Series of specially commissioned articles, Nature Reviews Molecular Cell Biologyreports on our current understanding of the molecular mechanisms that underlie a range of common human disorders, explores possible therapeutic targets and treatments, and discusses new technologies and resources to study disease mechanisms.

  • Focus |

    This special Focus issue describes how diverse cellular systems can be modelled through a combination of high-throughput experimental data and mathematical and computational approaches.

  • Milestone |

    Milestones in Gene Expression is a collaborative project involving six journals - Nature,Nature Cell Biology,Nature Genetics,Nature Reviews Genetics,Nature Reviews Molecular Cell BiologyandNature Structural & Molecular Biology- and celebrates almost 50 years of discoveries in the field of transcription and chromatin.

  • Focus |

    Epigenetics — the study of heritable changes in gene expression or function that occur without a change in the DNA sequence itself — is proving to have an increasingly important role in both human development and disease, particularly cancer.

  • Focus |

    When talking about RNAi, it is difficult to separate biology from technology. And so this Collection on RNA interference includes Reviews and Research Highlights on both aspects of this topic.

  • Focus |

    The field of RNA is defined by the many different RNA species that exist in nature. The most well-known and most diverse species — messenger RNA — carry the genetic code, which is to be translated into proteins.

  • Focus |

    This Collection on systems biology, which contains a selection of recent reviews, perspectives and research highlights, is designed to provide an introduction to this emerging cross-disciplinary field.

  • Series |

    Throughout 2005, a series of articles on Developmental Cell Biology will appear in Nature Reviews Molecular Cell Biology. The present-day study of developmental biology involves a multidisciplinary approach, with imaging, genetic analysis, biochemistry, molecular and cell biology techniques all contributing to the rapid progress that is being made in this area. We hope that this series of articles, from a cell biology perspective, will give you a taste of the diversity of topics that form part of this rapidly moving field.

  • Focus |

    The availability of whole genome sequences for many organisms has resulted in a rush to elucidate the function of the products of these genomes and their role in health and disease. But deciphering the complexity of the proteome is a daunting task, and the application of proteomics is still very much in its infancy.

  • Focus |

    Historically, plant cell biology has been studied using more traditional genetic approaches, but more recently, biochemistry, and state-of-the-art imaging and other cell biology techniques have contributed to the wealth of exciting data in this broad field.