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In gastroenterology, ChatGPT and large language models (LLMs) can assist clinicians in various tasks but also have several shortcomings. Although LLMs have great potential to assist clinicians in health care, they should be used as a tool to support, rather than replace, human expertise.
A new study has found that a strain of the gut bacterium Lactiplantibacillus plantarum activates a NOD2–type I interferon–insulin-like growth factor 1 pathway in young mice to partially protect against the deleterious growth effects of a diet deficient in protein and fat. Could live biotherapeutic products or their derivatives unlock the full potential of nutritional interventions against childhood stunting?
In this Review, Llovet and colleagues discuss advances in our knowledge of the pathogenesis and clinical management of nonalcoholic steatohepatitis-related hepatocellular carcinoma. They also discuss future prospects and unmet needs.
The treatment landscape of inflammatory bowel disease (IBD) is constantly evolving, including among pregnant women and those who wish to become pregnant. This Review provides a detailed update on the management of patients with IBD during pregnancy and breastfeeding.
This Review provides an overview of the global epidemiology and burden of hepatitis B virus (HBV) infection, identifying gaps in the HBV care cascade and proposing some solutions to help reach the goal of WHO to eliminate HBV as a public health threat by 2030.
Macrophages are critical for maintaining intestinal homeostasis, yet are implicated in chronic intestinal inflammation. This Review provides detailed insights into the biology of macrophages in the context of inflammatory bowel disease and discusses future perspectives.
