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Functional dyspepsia

No short cut to distinguish organic diseases from dyspepsia

Functional dyspepsia has been defined in various ways, but the diagnostic yield of these definitions has not been well validated. Ford et al. have now reported the diagnostic yield of the Rome III criteria, which was not superior to previous definitions. The study also indicates the difficulty of excluding organic diseases using these criteria.

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References

  1. Brook, R. A. et al. Functional dyspepsia impacts absenteeism and direct and indirect costs. Clin. Gastroenterol. Hepatol. 8, 498–503 (2010).

    Google Scholar 

  2. Talley, N. J. et al. Functional gastroduodenal disorders. Gut 45 (Suppl. 2), II37–II42 (1999).

    Google Scholar 

  3. Tack, J. et al. Functional gastroduodenal disorders. Gastroenterology 130, 1466–1479 (2006).

    Google Scholar 

  4. Ford, A. C. et al. The Rome III Criteria for the diagnosis of functional dyspepsia in secondary care are not superior to previous definitions. Gastroenterology http://dx.doi.org/10.1053/j.gastro.2014.01.014.

  5. Vakil, N., van Zanten, S. V., Kahrilas, P., Dent, J. & Jones, R. The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am. J. Gastroenterol. 101, 1900–1920 (2006).

    Google Scholar 

  6. Nagahara, A. et al. Clinical feature of asymptomatic reflux esophagitis in patients who underwent upper gastrointestinal endoscopy. J. Gastroenterol. Hepatol. 27 (Suppl. 3), 53–57 (2012).

    Google Scholar 

  7. Gonlachanvit, S. Are rice and spicy diet good for functional gastrointestinal disorders? J. Neurogastroenterol. Motil. 16, 131–138 (2010).

    Google Scholar 

  8. Fock, K. M. et al. Second Asia-Pacific Consensus Guidelines for Helicobacter pylori infection. J. Gastroenterol. Hepatol. 24, 1587–1600 (2009).

    Google Scholar 

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Correspondence to Hiroto Miwa.

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The author declares no competing financial interests.

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Miwa, H. No short cut to distinguish organic diseases from dyspepsia. Nat Rev Gastroenterol Hepatol 11, 207–208 (2014). https://doi.org/10.1038/nrgastro.2014.19

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