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Rhythmic electrical slow waves generate the contractions fundamental to gastrointestinal motility and certain disorders. In this Perspective, Sanders and colleagues discuss the application of slow-wave extracellular recording techniques to gastrointestinal organs and how mechanical artefacts might contaminate these recordings and confound interpretation.
Although IBS and IBD are regarded as distinct entities, they do share features and symptoms. This Perspective explores the overlap between the two conditions, debating whether consideration of the similarities between IBS and IBD could improve treatment and inform future research.
The many gaps in our knowledge and understanding of HBV infection hampers our ability to develop and achieve a cure on a global scale. In this Perspective, Fabien Zoulim and colleagues propose the development of an international group consisting of four working groups (virology, immunology, innovative tools and clinical trials) to tackle the big questions and make important steps towards eradicating this disease.
