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This article highlights two cases of massive lower gastrointestinal bleeding in patients on dialysis after rejection of kidney–pancreas transplants. One patient did not have the transplanted organ removed and eventually exsanguinated, while the second patient, whose rejected pancreas was removed, survived complications and did well. The cases illustrate that arterio-enteric bleeding should be included in the differential diagnosis of patients with rejected pancreatic transplants.
This article highlights the case of a 74-year-old Caucasian female who presented with jaundice, clay-colored stools, diarrhea, and fatigue of 3 months' duration, accompanied by a weight loss of 6.8 kg. The results of initial investigations were interpreted as primary sclerosing cholangitis, but futher investigation revealed lytic and and blastic bone lesions. A sacral bone biopsy established the diagnosis of systemic mastocytosis.