On page 422 of this Review it is incorrectly stated that: “Further evidence for MeCP2 function as a regulator of BDNF expression was provided by postmortem studies of brains from patients with Rett syndrome.” In fact, no evidence has yet been provided that MeCP2 functions as a regulator of BDNF expression in the brains of patients with Rett syndrome. This error could also lead to misinterpretation of the following sentence: “BDNF levels were found to be higher in the 'Rett-syndrome-affected' prefrontal cortex and lower in the 'Rett-syndrome-spared' occipital cortex, particularly after childhood.” The study that is cited analysed only tissue from healthy brains; the sentence refers to BDNF levels in the areas that would be expected to be affected in individuals with Rett syndrome.
The authors apologize for the error.
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The online version of the original article can be found at 10.1038/nrg1878
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Bienvenu, T., Chelly, J. Erratum: Molecular genetics of Rett syndrome: when DNA methylation goes unrecognized. Nat Rev Genet 7, 583 (2006). https://doi.org/10.1038/nrg1913
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DOI: https://doi.org/10.1038/nrg1913
