Review
Nature Reviews Genetics 4, 346-358 (May 2003) | doi:10.1038/nrg1066
Progress and problems with the use of viral vectors for gene therapy
Clare E. Thomas1, Anja Ehrhardt1 & Mark A. Kay1 About the authors
Abstract
Gene therapy has a history of controversy. Encouraging results are starting to emerge from the clinic, but questions are still being asked about the safety of this new molecular medicine. With the development of a leukaemia-like syndrome in two of the small number of patients that have been cured of a disease by gene therapy, it is timely to contemplate how far this technology has come, and how far it still has to go.
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Author affiliations
- Departments of Pediatrics and Genetics, Stanford University School of Medicine, Stanford, California 94305, USA.
Correspondence to: Mark A. Kay1 Email: markay@stanford.edu
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