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Research Highlights

Nature Reviews Genetics 10, 510 (1 August 2009) | doi:10.1038/nrg2646

Technology: The sequencing game

Tanita Casci

A new approach to pooling DNA samples promises to increase the number of templates that can be sequenced in a single experiment from a few dozen to over 100,000. This 'DNA Sudoku' method, named after the logic puzzle, will offer substantial cost savings to high-throughout sequencing and efficient medical genotyping.