A novel study published in The Lancet suggests a U-shaped association between HbA1c levels and mortality in patients with type 2 diabetes mellitus. But is a revision of current guidelines to include a minimum HbA1c target advisable on the basis of these findings?
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S. Ali declares no competing interests. V. A. Fonseca declares an association with the following companies: AstraZeneca (research support), Daiichi Sankyo (research support/honoraria for consulting and lectures), Eli Lilly (research support/honoraria for consulting and lectures), GlaxoSmithKline (research support/honoraria for consulting and lectures), Novartis (research support/honoraria for consulting and lectures), Novo Nordisk (research support/honoraria for consulting and lectures), Sanofi-Aventis (research support/honoraria for consulting and lectures), Takeda (research support/honoraria for consulting and lectures).
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Ali, S., Fonseca, V. Low HbA1c levels and mortality in type 2 diabetes mellitus. Nat Rev Endocrinol 6, 359–360 (2010). https://doi.org/10.1038/nrendo.2010.69
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DOI: https://doi.org/10.1038/nrendo.2010.69
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