Articles in 2021

Penile cancer is a rare disease for which early diagnosis is crucial to avoid poor prognosis and outcomes. This PrimeView highlights the epidemiology, diagnosis, mechanisms and management of penile cancer and accompanies the Primer on this topic by Thomas and colleagues.

This Primer discusses the epidemiology of penile cancer and mechanisms underlying its development, including HPV infection. The authors explain contemporary and possible future diagnostic and management approaches in localized and advanced disease and highlight important considerations around the quality of life of affected patients.

Prostate cancer is the second most common cancer in men. This PrimeView describes epidemiology, diagnosis and management of the disease and highlights the mechanisms of its development.

Prostate cancer is the second most common cancer and one of the leading causes of cancer-associated death in men. This Primer summarizes the epidemiology, mechanisms and diagnosis of prostate cancer, discusses treatment based on disease stage and effects on quality of life, and highlights ongoing and future research areas.

The incidence of Hepatocellular carcinoma (HCC) is increasing worldwide. This PrimeView describes the epidemiology, mechanisms and diagnosis of HCC as well as highlights the major advancements in its management.

Hepatocellular carcinoma (HCC), the most common type of primary liver cancer, is one of the leading causes of cancer-related death in the world. This Primer summarizes the current knowledge on the epidemiology, pathogenetic mechanisms and diagnosis of HCC and provides an update on key advancements in the management of this disease.

Small-cell lung cancer is a rapidly proliferating cancer with a poor prognosis, and is strongly associated with exposure to tobacco carcinogens. This PrimeView highlights the epidemiology, pathogenesis, diagnosis and management of the disease.

Homeless people face tremendous social and structural barriers to health care that contribute to high morbidity and mortality. Here, the authors discuss that collaborations between health systems and social services are needed to improve health and well-being in this population.

Small-cell lung cancer is a rapidly proliferating cancer with a poor prognosis and is strongly associated with exposure to tobacco carcinogens. This Primer describes the epidemiology, pathogenesis and diagnosis of the disease as well as the current management approaches and new therapies that might improve outcomes.

Tendinopathy describes a spectrum of changes that occur in a tendon, leading to pain and impaired function. This PrimeView accompanies the Primer article on Tendinopathy by Millar and colleagues and highlights its epidemiology, mechanisms, diagnosis, and management.

Tendinopathy is a multifaceted pathology of the tendon, characterized by pain and reduced function. This Primer summarizes the epidemiology, pathophysiology, diagnosis and the latest insights in the management of this disorder. Finally, the authors discuss the outstanding issues that will help achieve better outcomes in patients with tendinopathy.