PrimeViews

This PrimeView highlights the pathogenesis of monogenic diabetes, a group of predominantly early-onset disorders that are caused by single genetic alterations.

This PrimeView summarizes the pathophysiology of fetal alcohol spectrum disorders, a group of conditions that occur in children exposed prenatally to alcohol.

This PrimeView highlights the diagnosis of pre-eclampsia and summarizes its epidemiology, pathophysiology and management. It accompanies the Primer on this topic by Dimitriadis and colleagues.

This PrimeView highlights the pathophysiology of medication overuse headache, a secondary headache disorder caused by overuse of acute headache medications by individuals with underlying headache disorders.

This PrimeView highlights the mechanisms of ichthyosis and summarizes its epidemiology, diagnosis and management. It accompanies the Primer on this topic by Gutiérrez-Cerrajero and colleagues.

This PrimeView summarizes strategies for the prevention of alcohol use disorders (AUDs) and accompanies the Primer on Hazardous drinking and AUDs by MacKillop and colleagues.

This PrimeView highligths Burkitt lymphoma, an aggressive form of B cell lymphoma that can affect children and adults. Most patients with BL can be treated successfully with chemotherapy, but new therapeutic approaches are required for relapsed or refractory disease.

Osteosarcoma is the most common primary malignant tumour of the bone, but can also arise as a secondary tumour in individuals with a history of cancer. This PrimeView highlights the pathomechanism of these cancers.

This PrimeView highlights the pathophysiology of myelodysplastic syndromes and summarizes their epidemiology, diagnosis and management. It accompanies the Primer on this topic by Liang and colleagues.

This PrimeView highlights the management of asplenia and spleen hypofunction and summarizes their epidemiology, diagnosis and mechanisms. It accompanies the Primer on this topic by Lenti and colleagues.

This PrimeView highlights the mechanisms of gallbladder cancer and summarizes its epidemiology, diagnosis and management. It accompanies the Primer on this topic by Roa and colleagues.

Fracture-related infection is a common fracture complication that prolongs healing and can increase morbidity and mortality. This PrimeView highlights the pathophysiology of these infections.

Small round cell sarcomas are aggressive tumours of bone and soft tissue resulting mostly from gene fusions. This PrimeView highlights the diagnosis of these cancers.

This PrimeView highlights the mechanisms of adult-onset autoimmune diabetes and summarizes its epidemiology, diagnosis, management and outlook. It accompanies the Primer on this topic by Buzzetti and colleagues.

This PrimeView highlights the mechanisms or urticaria and summarizes its epidemiology, diagnosis and management. It accompanies the Primer on this topic by Kolkhir and colleagues.

This PrimeView highlights the pathophysiology, epidemiology, diagnosis, management and outlook of frozen shoulder.

This PrimeView highlights the underlying mechanism of multiple system atrophy (MSA), a synucleinopathy that affects several regions of the brain. This PrimeView accompanies the Primer on MSA by Poewe and colleagues.

This PrimeView highlights the pathophysiology of faecal incontinence in adults and summarizes its epidemiology, diagnosis and management. It accompanies the Primer on this topic by Bharucha and colleagues.

This PrimeView summarizes the mechanisms of spinal muscular atrophy, a progressive disorder that manifests as muscle atrophy and weakness of limb, bulbar, trunk and respiratory muscles.

This PrimeView highlights the mechanisms underlying chronic wounds and summarizes the epidemiology, diagnosis and management of these wounds. It accompanies the Primer on this topic by Falanga and colleagues.