FIGURE 1 | Gene-family distribution of current drugs per drug substance.
From the following article:
How many drug targets are there?
John P. Overington, Bissan Al-Lazikani and Andrew L. Hopkins
Nature Reviews Drug Discovery 5, 993-996 (December 2006)
doi:10.1038/nrd2199
The family share as a percentage of all FDA-approved drugs is displayed for the top ten families. Beyond the ten most commonly drugged families, there are a further 120 domain families or singletons for which only a few drugs have been successfully launched. Data based on 1,357 dosed components from >20,000 approved products, FDA, December 2005. GPCR, G-protein-coupled receptor.
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