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Confocal image of mouse dentate gyrus showing surviving cells (BrdU, red) that co-expressed markers of neuronal development (doublecortin, green; and calretinin, blue). Co-labeling of BrdU, doublecortin and calretinin identifies new neurons that survived following a chronic melatonin treatment. Scale bar 100 μm. Courtesy of Gerd Kempermann, M.D. Research Center for Regenerative Therapies Dresden, Germany.