Nanomechanical sensors can now detect femtomolar concentrations of analytes within minutes without the need to passivate the underlying cantilever surface.
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Shekhawat, G., Dravid, V. Microcantilevers to lift biomolecules. Nature Nanotech 10, 830–831 (2015). https://doi.org/10.1038/nnano.2015.187
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DOI: https://doi.org/10.1038/nnano.2015.187