News & Views in 2023

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  • Almost twenty years after it was first linked to control of Mycobacterium tuberculosis in macrophages, autophagy retakes centre stage, as shown in murine models and human cells.

    • Vojo Deretic
    • Fulong Wang
    News & Views
  • Bladder epithelial cells exposed to uropathogenic Escherichia coli infection have long-lasting epigenetic modifications linked with inflammation that influence host susceptibility to subsequent infections.

    • Soumitra Mohanty
    • John Kerr White
    • Annelie Brauner
    News & Views
  • Dysbiosis of the gut microbiome confers alterations in appetitive and metabolic regulation of body weight in anorexia nervosa in humans and mice.

    • Tom Hildebrandt
    • Deena Peyser
    News & Views
  • Phage-encoded endolysins released from neighbouring infected bacterial cells can confer a temporary resistance to phage infection by mediating the reversible loss of the cell wall.

    • Thomas G. Denes
    News & Views
  • Mycobacterium abscessus requires high levels of biotin biosynthesis during infection, because this vitamin enables key adaptations to the alkaline lung airway environment through fatty acid remodelling that increases fluidity of the cell envelope.

    • Wassim Daher
    • Laurent Kremer
    News & Views
  • Candidatus Methanoperedens nitroreducens’, an anaerobic methanotrophic archaeon, sectors itself into two morphologically and functionally distinct populations that enable adaptation and cross-species interactions in a dynamic bioreactor ecosystem.

    • Lisa Y. Stein
    News & Views
  • New World arenaviruses are pathogens capable of zoonotic infections that cause viral haemorrhagic fevers, which are frequently lethal in humans. However, a recombinant live-attenuated pentavalent vaccine shows promising efficacy against infection.

    • Jérémie Prévost
    • Bryce M. Warner
    • David Safronetz
    News & Views