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Since a diagnostic test for hepatitis C became available in 1990, several industrialized nations have been quick to implement it in order to prevent transfusions of contaminated blood. Less clear is the policy for dealing with transfusion recipients that received blood prior to this date.
A novel anti-HIV strategy uses modified chemokines (intrakines), trapped within the endoplasmic reticulum, to block expression of HIV co-receptors on the host cell surface (pages 1110–1116).
A novel mechanism used by pathogenic mycobacteria to enter macrophages (in low complement environments) may provide a new therapeutic target for the treatment of tuberculosis.
Infusion of aging monkeys with growth hormone promotes proliferation of mammary epithelia, suggesting caution in treating the elderly with growth hormone supplements (pages 1141–1144).
