Stitches offer a suitable means of sealing up simple wounds. But when it comes to suturing tissues inside the body, the existing methods for closing wounds fall short. Elie Dolgin meets scientists taking inspiration from nature to develop the next generation of surgical adhesives.
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References
Cho, W.K. et al. Proc. Natl. Acad. Sci. USA 109, 21289–21294 (2012).
Matos-Pérez, C.R., White, J.D. & Wilker, J.J. J. Am. Chem. Soc. 134, 9498–9505 (2012)
Lee, B., Dalsin, J.L. & Messersmith, P.B. in Biological Adhesives (eds. Smith, A.M. & Callow, J.A.) 257–278 (Springer-Verlag, Berlin, 2006).
Brubaker, C.E., Kissler, H., Wang, L.J., Kaufman, D.B. & Messersmith, P.B. Biomaterials 31, 420–427 (2010).
Nakano, M., Shen, J.R. & Kamino, K. Biomacromolecules 8, 1830–1835 (2007).
Shao, H., Bachus, K.N. & Stewart, R.J. Macromol. Biosci. 9, 464–471 (2009).
Winslow, B.D., Shao, H., Stewart, R.J. & Tresco, P.A. Biomaterials 31, 9373–9381 (2010).
Mann, L.K. et al. Acta Biomater. 8, 2160–2165 (2012).
Haller, C.M. et al. Acta Biomater. 8, 4365–4370 (2012).
Mahdavi, A. et al. Proc. Natl. Acad. Sci. USA 105, 2307–2312 (2008).
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Dolgin, E. The Sticking Point. Nat Med 19, 124–125 (2013). https://doi.org/10.1038/nm0213-124
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DOI: https://doi.org/10.1038/nm0213-124
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