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| A series of articles highlighting the major biomedical achievements of the past decade. |
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| Editorial | Top |
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The sounds of silence p653
doi:10.1038/nm0704-653
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| News | Top |
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Courts crack down on drug marketing strategies p655
Tinker Ready
doi:10.1038/nm0704-655a
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Europe kicks off prion research network p655
Xavier Bosch
doi:10.1038/nm0704-655b
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China's biomedical research takes flight in new directions p656
David Cyranoski
doi:10.1038/nm0704-656a
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Mexico reverses ban on stem cell research p656
Claudia Orellana
doi:10.1038/nm0704-656b
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Scientists rip US for cutbacks to global AIDS summit p657
Peter Vermij
doi:10.1038/nm0704-657a
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NIH mulls plan to lower cost of AIDS drugs p657
Paroma Basu
doi:10.1038/nm0704-657b
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(175K)
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News In Brief p658
doi:10.1038/nm0704-658
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Profile: Clive Svendsen p659
Paroma Basu
doi:10.1038/nm0704-659
Abstract | Full text | PDF
(148K)
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Nicotine fix pp660 - 661
Apoorva Mandavilli
doi:10.1038/nm0704-660
Abstract | Full text | PDF
(332K)
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| Correspondence | Top |
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Mouse models of visual deficits p663
Nilanjana Sengupta
& Sergio Caballero
doi:10.1038/nm0704-663a
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(64K)
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Reply to "Mouse models of visual deficits" p663
Jayakrishna Ambati, Akshay Anand, Eiji Sakurai, William A Kuziel, Barrett J Rollins
& Balamurali K Ambati
doi:10.1038/nm0704-663b
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(64K)
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| Commentary | Top |
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Building global networks for human diseases: genes and populations pp665 - 667
Hans-E Hagen
& Jan Carlstedt-Duke
doi:10.1038/nm0704-665
Abstract | Full text | PDF
(76K)
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| Book Reviews | Top |
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Who really wore the pants? p669
Reviewed by: Londa Schiebinger
doi:10.1038/nm0704-669
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(119K)
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Into the fire p670
Reviewed by: Steven E Wolf
doi:10.1038/nm0704-670
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(85K)
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| News and Views | Top |
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Alchemy in the liver: fact or fusion? pp671 - 672
George Q Daley
doi:10.1038/nm0704-671
Abstract | Full text | PDF
(203K)
See also: Letter by Willenbring et al. |
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Not asleep, not quite awake pp673 - 674
J Gregor Sutcliffe
& Luis de Lecea
doi:10.1038/nm0704-673
Abstract | Full text | PDF
(210K)
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Sleep smarts p674
Juan Carlos López
doi:10.1038/nm0704-674
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(177K)
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Brain on steroids resists neurodegeneration pp675 - 676
Mark P Burns
& Karen Duff
doi:10.1038/nm0704-675
Abstract | Full text | PDF
(146K)
See also: Article by Griffin et al. |
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Glycosylation eases muscular dystrophy pp676 - 677
Francesco Muntoni, Martin Brockington
& Susan C Brown
doi:10.1038/nm0704-676
Abstract | Full text | PDF
(458K)
See also: Article by Barresi et al. |
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Cannabinoids cool the intestine pp678 - 679
George Kunos
& Pál Pacher
doi:10.1038/nm0704-678
Abstract | Full text | PDF
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APCs size up antigens pp679 - 681
Keith S Bahjat
& Stephen P Schoenberger
doi:10.1038/nm0704-679
Abstract | Full text | PDF
(451K)
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Cellular energy sensor balances the scales pp681 - 682
Caroline J Small, David Carling
& Stephen R Bloom
doi:10.1038/nm0704-681
Abstract | Full text | PDF
(330K)
See also: Article by Kim et al. |
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Research Highlights p683
doi:10.1038/nm0704-683
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(83K)
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| Review | Top |
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The neurobiology of antiepileptic drugs for the treatment of nonepileptic conditions pp685 - 692
Michael A Rogawski
& Wolfgang Löscher
Published online: 01 July 2004 | doi:10.1038/nm1074
Abstract | Full text | PDF
(430K)
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| Brief Communication | Top |
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Injection of recombinant human type VII collagen restores collagen function in dystrophic epidermolysis bullosa pp693 - 695
David T Woodley, Douglas R Keene, Tom Atha, Yi Huang, Kathi Lipman, Wei Li
& Mei Chen
Published online: 13 June 2004 | doi:10.1038/nm1063
Abstract | Full text | PDF
(803K)
| Supplementary Information |
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| Articles | Top |
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LARGE can functionally bypass  -dystroglycan glycosylation defects in distinct congenital muscular dystrophies pp696 - 703
Rita Barresi, Daniel E Michele, Motoi Kanagawa, Hollie A Harper, Sherri A Dovico, Jakob S Satz, Steven A Moore, Wenli Zhang, Harry Schachter, Jan P Dumanski, Ronald D Cohn, Ichizo Nishino
& Kevin P Campbell
Published online: 06 June 2004 | doi:10.1038/nm1059
Abstract | Full text | PDF
(2,719K)
| Supplementary Information
See also: News and Views by Muntoni et al. |
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Niemann−Pick type C disease involves disrupted neurosteroidogenesis and responds to allopregnanolone pp704 - 711
Lisa D Griffin, Wenhui Gong, Lucie Verot
& Synthia H Mellon
Published online: 20 June 2004 | doi:10.1038/nm1073
Abstract | Full text | PDF
(2,343K)
See also: News and Views by Burns & Duff |
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Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling pp712 - 718
Makoto Inoue, Md Harunor Rashid, Ryousuke Fujita, James J A Contos, Jerold Chun
& Hiroshi Ueda
Published online: 13 June 2004 | doi:10.1038/nm1060
Abstract | Full text | PDF
(3,165K)
| Supplementary Information |
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Apolipoprotein E promotes astrocyte colocalization and degradation of deposited amyloid- peptides pp719 - 726
Milla Koistinaho, Suizhen Lin, Xin Wu, Michail Esterman, Deanna Koger, Jeffrey Hanson, Richard Higgs, Feng Liu, Seema Malkani, Kelly R Bales
& Steven M Paul
Published online: 13 June 2004 | doi:10.1038/nm1058
Abstract | Full text | PDF
(2,484K)
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Anti-obesity effects of -lipoic acid mediated by suppression of hypothalamic AMP-activated protein kinase pp727 - 733
Min-Seon Kim, Joong-Yeol Park, Cherl Namkoong, Pil-Geum Jang, Je-Won Ryu, Hai-Sun Song, Ji-Young Yun, Il-Seong Namgoong, Joohun Ha, In-Sun Park, In-Kyu Lee, Benoit Viollet, Jang Hyun Youn, Hong-Kyu Lee
& Ki-Up Lee
Published online: 13 June 2004 | doi:10.1038/nm1061
Abstract | Full text | PDF
(1,032K)
| Supplementary Information
See also: News and Views by Small et al. |
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| Letters | Top |
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Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3 pp734 - 738
Jane K Howard, Belinda J Cave, Laura J Oksanen, Iphigenia Tzameli, Christian Bjørbæk
& Jeffrey S Flier
Published online: 27 June 2004 | doi:10.1038/nm1072
Abstract | Full text | PDF
(312K)
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Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity pp739 - 743
Hiroyuki Mori, Reiko Hanada, Toshikatsu Hanada, Daisuke Aki, Ryuichi Mashima, Hitomi Nishinakamura, Takehiro Torisu, Kenneth R Chien, Hideo Yasukawa
& Akihiko Yoshimura
Published online: 20 June 2004 | doi:10.1038/nm1071
Abstract | Full text | PDF
(747K)
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Myelomonocytic cells are sufficient for therapeutic cell fusion in liver pp744 - 748
Holger Willenbring, Alexis S Bailey, Mark Foster, Yassmine Akkari, Craig Dorrell, Susan Olson, Milton Finegold, William H Fleming
& Markus Grompe
Published online: 13 June 2004 | doi:10.1038/nm1062
Abstract | Full text | PDF
(1,384K)
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| Technical Report | Top |
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Isolated small intestinal segments support auxiliary livers with maintenance of hepatic functions pp749 - 753
Brigid Joseph, Ekaterine Berishvili, Daniel Benten, Vinay Kumaran, Ekaterine Liponava, Kuldeep Bhargava, Christopher Palestro, Zurab Kakabadze
& Sanjeev Gupta
Published online: 30 May 2004 | doi:10.1038/nm1057
Abstract | Full text | PDF
(2,314K)
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| Errata | Top |
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ERRATUM: PGC-1 promotes insulin resistance in liver through PPAR--dependent induction of TRB-3 p755
Seung-Hoi Koo, Hiroaki Satoh, Stephan Herzig, Chih-Hao Lee, Susan Hedrick, Rohit Kulkarni, Ronald M Evans, Jerrold Olefsky
& Marc Montminy
doi:10.1038/nm0704-755a
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(186K)
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ERRATUM: Reciprocal CD40 signals through p38MAPK and ERK-1/2 induce counteracting immune responses p755
Ram Kumar Mathur, Amit Awasthi, Pallavi Wadhone, Boppana Ramanamurthy
& Bhaskar Saha
doi:10.1038/nm0704-755b
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(186K)
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ERRATUM: Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling p755
Makoto Inoue, Md Harunor Rashid, Ryousuke Fujita, James J A Contos, Jerold Chun
& Hiroshi Ueda
doi:10.1038/nm0704-755c
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(186K)
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| New on the Market | Top |
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New on the market p757
doi:10.1038/nm0704-757
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(259K)
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