New work shows that CARD9, the recently identified member of the caspase recruitment domain–containing family, directly interacts with the cytoplasmic protein Nod2 in the detection of intracellular bacteria.
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Underhill, D., Shimada, T. A pair of 9s: it's in the CARDs. Nat Immunol 8, 122–124 (2007). https://doi.org/10.1038/ni0207-122
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DOI: https://doi.org/10.1038/ni0207-122