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CCR5 and its ligands: a new axis of evil?

Many additional effects in HIV pathogenesis are now described for the chemokine receptor CCR5, long recognized as an important coreceptor for HIV, and its ligand CCL3L1.

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Figure 1: The CCR5-CCL3L1 axis in HIV pathogenesis and in health.

Kim Caesar

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Lederman, M., Sieg, S. CCR5 and its ligands: a new axis of evil?. Nat Immunol 8, 1283–1285 (2007). https://doi.org/10.1038/ni1207-1283

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