Lymphocytes continuously recirculate throughout the body. Evidence now suggests chemokine receptor CCR7 actively controls lymphocyte entry into afferent lymphatic vessels.
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Lira, S. A passport into the lymph node. Nat Immunol 6, 866–868 (2005). https://doi.org/10.1038/ni0905-866
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DOI: https://doi.org/10.1038/ni0905-866