Nature Immunology 6, 1069 - 1070 (2005)
doi:10.1038/ni1105-1069
TH-17: a giant step from TH1 and TH2Thomas A Wynn
Thomas A. Wynn is at the National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA. twynn@niaid.nih.gov
CD4+ T cells have been classically separated into two dominant effector populations: T helper types 1 and 2. Two new studies suggest that T cells producing interleukin 17 constitute a previously unknown lineage of CD4+ T cells.
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