Growing evidence indicates immune and nervous systems use common mechanisms to mediate intercellular communication. Adding to this list is the discovery that dendritic cells modulate T cell interactions through expression of the neuronal receptor plexin-A1, which is regulated by the transcriptional activator CIITA.
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Reith, W. ComPLEXIN new targets for CIITA. Nat Immunol 4, 819–820 (2003). https://doi.org/10.1038/ni0903-819
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DOI: https://doi.org/10.1038/ni0903-819
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