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Nature Immunology  4, 304 - 306 (2003)
doi:10.1038/ni0403-304

Twenty-first century Foxp3

Anne O'Garra1 & Paulo Vieira2

1  Division of Immunoregulation, The National Institute for Medical Research (NIMR), NW7 1AA London, United Kingdom.

2  Unité du Développement des Lymphocytes (CNRS URA 1961), Institut Pasteur, 25 Rue du Docteur Roux, 757015 Paris, France.

Correspondence should be addressed to Anne O'Garra
aogarra@nimr.mrc.ac.uk
The transcription factor(s) controlling TReg cell development are not definitely known. The finding that these cells specifically express Foxp3 provides a better understanding of their development and function at the molecular level.

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Nature Immunology
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EISSN: 1529-2916
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