Volume 17 Issue 2, October 1997

Chloride channels cough up

• Rajesh V. Thakker

The maddening hunt for madness genes

• Steven O. Moldin

Molecular evolution—who is in the driver's seat?

• James F. Crow

On the TRAIL from p53 to apoptosis?

• Michael Kastan

A searchlight through the fog

• Alan F. Wright

Touching base

A human compound heterozygote for two MLH1 missense mutations

• Peter Hackman
• Pia Tannergård
• Annika Lindblom

Sex–dependent rearrangements resulting in CMT1A and HNPP

• Judith Lopes
• Antoon Vandenberghe
• Eric LeGuern

Early-onset type-ll diabetes mellitus (MODY4) linked to IPF1

• Doris A. Staffers
• Jorge Ferrer
• Joel F. Habener

Mutations in RPE65 cause Leber's congenital amaurosis

• Françoise Marlhens
• Corinne Bareil
• Christian P. Hamel

KILLER/DR5 is a DNA damage–inducible p53–regulated death receptor gene

• Gen Sheng Wu
• Timothy F. Burns
• Wafik S. El-Deiry

PTEN1 is frequently mutated in primary endometrial carcinomas

• Dehe Kong
• Akihiko Suzuki
• Akira Horii

Genetic interaction between HAP1/REF-1 and p53

• Lisiane B. Meira
• David L. Cheo
• Errol C. Friedberg

Mutations in transcriptional regulator ATRX establish the functional significance of a PHD-like domain

• Richard J. Gibbons
• Satvinder Bachoo
• Douglas R. Higgs

Diabetes, dependence, asymptotics, selection and significance

• Augustine Kong
• Mike Frigge
• Nancy J. Cox

A novel gene encoding an SH3 domain protein is mutated in nephronophthisis type 1

• Friedhelm Hildebrandt
• Edgar Otto
• Matthias Brandis

Homologous recombination of a flanking repeat gene cluster is a mechanism for a common contiguous gene deletion syndrome

• Ken-Shiung Chen
• Prasad Manian
• James R. Lupski

Positional cloning of the gene associated with X-linked juvenile retinoschisis

• Christian G. Sauer
• Andrea Gehrig
• Bernhard H.F. Weber

Mutations in the chloride channel gene, CLCNKB, cause Bartter's syndrome type III

• David B. Simon
• Ranjit S. Bindra
• Richard P. Lifton

Perinatal lethality with kidney and pancreas defects in mice with a targetted Pkd1 mutation

• Weining Lu
• Bernard Peissel
• Jing Zhou

Male–driven evolution of DNA sequences in birds

• Hans Ellegren
• Anna-Karin Fridolfsson

Identification of PAHX, a Refsum disease gene

• Stephanie J. Mihalik
• James C. Morrell
• Stephen J. Gould

Refsum disease is caused by mutations in the phytanoyl–CoA hydroxylase gene

• Gerbert A. Jansen
• Rob Oftnan
• Ronald J.A. Wanders

Mutations in RPE65 cause autosomal recessive childhood–onset severe retinal dystrophy

• Su-min Gu
• Debra A. Thompson
• Andreas Gal

Mutation of the gene encoding cellular retinaldehyde–binding protein in autosomal recessive retinitis pigmentosa

• Marion A. Maw
• Breandan Kennedy
• Michael J. Denton

The genetic and functional basis of isolated 17,20–lyase deficiency

• David H. Geller
• Richard J. Auchus
• Walter L. Miller

Increased stress response and β–phenylethylamine in MAOB–deficient mice

• Joseph Grimsby
• Miklos Toth
• Jean C. Shih

Drosophila CBP is required for dorsal–dependent twist gene expression

• Hiroshi Akimaru
• De-Xing Hou
• Shunsuke Ishii

Aconitase and mitochondrial iron–sulphur protein deficiency in Friedreich ataxia

• Agnès Rötig
• Pascale de Lonlay
• Pierre Rustin

Targetting of the gene encoding fibrillin–1 recapitulates the vascular aspect of Marfan syndrome

• Lygia Pereira
• Konstantinos Andrikopoulos
• Francesco Ramirez

Cre–mediated chromosome loss in mice

• Mark Lewandoski
• Gail R. Martin

Deregulation of MUM1/IRF4 by chromosomal translocation in multiple myeloma

• Shinsuke Iida
• Pulivarthi H. Rao
• Riccardo Dalla-Favera

Human telomeres contain two distinct Myb–related proteins, TRF1 and TRF2

• Dominique Broccoli
• Agata Smogorzewska
• Titia de Lange

Telomeric localization of TRF2, a novel human telobox protein

• Thomas Bilaud
• Christine Brun
• Eric Gilson

Mutations in the plakophilin 1 gene result in ectodermal dysplasia/skin fragility syndrome

• John A. McGrath
• James R. McMillan
• Robin A.J. Eady

Autumn days, purple haze