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Nature Genetics
ISSUE
August 2006, Volume 38 No 8
Editorial
Correspondence
News and Views
Research Highlights
Brief Communications
Articles
Letters
Erratum
Corrigendum
About the cover
Editorial Top
The germinating seed of Arab genomics p851
doi:10.1038/ng0806-851
Abstract | Full text | PDF (80K)
Correspondence Top
TranscriptSNPView: a genome-wide catalog of mouse coding variation p853
Fiona Cunningham, Daniel Rios, Mark Griffiths, James Smith, Zemin Ning, Tony Cox, Paul Flicek, Pablo Marin-Garcin, Javier Herrero, Jane Rogers, Louise van der Weyden, Allan Bradley, Ewan Birney & David J Adams
doi:10.1038/ng0806-853a
Full text | PDF (81K)  | Supplementary Information
Has the chimpanzee Y chromosome been sequenced? pp853 - 854
Jennifer F Hughes, Helen Skaletsky, Steve Rozen, Richard K Wilson & David C Page
doi:10.1038/ng0806-853b
Full text | PDF (177K)  | Supplementary Information
Reply to "Has the chimpanzee Y chromosome been sequenced?" pp854 - 855
Yoko Kuroki, Todd D Taylor, Hideki Noguchi, Takehiko Ito, Atsushi Toyoda, Yoshiyuki Sakaki & Asao Fujiyama
doi:10.1038/ng0806-854
Full text | PDF (162K)  | Supplementary Information
Normalization procedures and detection of linkage signal in genetical-genomics experiments pp855 - 856
Rohan B H Williams, Chris J Cotsapas, Mark J Cowley, Eva Chan, David J Nott & Peter F R Little
doi:10.1038/ng0806-855
Full text | PDF (1,182K)  | Supplementary Information
Reply to "Normalization procedures and detection of linkage signal in genetical-genomics experiments" pp856 - 858
Elissa J Chesler, Leonid Bystrykh, Gerald de Haan, Michael P Cooke, Andrew Su, Kenneth F Manly & Robert W Williams
doi:10.1038/ng0806-856
Full text | PDF (1,103K)
Reply to "Normalization procedures and detection of linkage signal in genetical-genomics experiments" pp858 - 859
Enrico Petretto, Jonathan Mangion, Stuart A Cook, Timothy J Aitman, Michal Pravenec, Herbert Schulz, Judith Fischer & Norbert Hubner
doi:10.1038/ng0806-858
Full text | PDF (695K)
Animal research and the search for understanding p859
Sandy Thomas
doi:10.1038/ng0806-859
Full text | PDF (89K)
News and Views Top
Closing in on complex traits pp861 - 862
Ariel Darvasi
doi:10.1038/ng0806-861
Abstract | Full text | PDF (397K)
See also: Article by Valdar et al.
From worm genetic networks to complex human diseases pp862 - 863
Howard Bussey, Brenda Andrews & Charles Boone
doi:10.1038/ng0806-862
Abstract | Full text | PDF (231K)
See also: Article by Lehner et al.
Context-dependent cancer risk pp864 - 865
Kent W Hunter
doi:10.1038/ng0806-864
Abstract | Full text | PDF (341K)
See also: Letter by To et al.
The difference between simple and complex leaves pp865 - 866
Elizabeth A Kellogg
doi:10.1038/ng0806-865
Abstract | Full text | PDF (322K)
See also: Letter by Hay & Tsiantis
Nucleic acid by-products and chronic inflammation pp866 - 867
Marta E Alarcón-Riquelme
doi:10.1038/ng0806-866
Abstract | Full text | PDF (1,424K)
See also: Article by Crow et al.  | Letter by Crow et al.
Touching base p869
doi:10.1038/ng0806-869
Full text | PDF (318K)
Research Highlights Top
Research Highlights p871
doi:10.1038/ng0806-871
Full text | PDF (62K)
Brief Communications Top
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility alleles pp873 - 875
Anthony Renwick, Deborah Thompson, Sheila Seal, Patrick Kelly, Tasnim Chagtai, Munaza Ahmed, Bernard North, Hiran Jayatilake, Rita Barfoot, Katarina Spanova, Lesley McGuffog, D Gareth Evans, Diana Eccles, Douglas F Easton, Michael R Stratton, The Breast Cancer Susceptibility Collaboration (UK) & Nazneen Rahman
Published online: 09 July 2006 | doi:10.1038/ng1837
Abstract | Full text | PDF (124K)  | Supplementary Information
Epigenetic asymmetry of imprinted genes in plant gametes pp876 - 878
José F Gutiérrez-Marcos, Liliana M Costa, Mauro Dal Prà, Stefan Scholten, Erhard Kranz, Pascual Perez & Hugh G Dickinson
Published online: 02 July 2006 | doi:10.1038/ng1828
Abstract | Full text | PDF (1,828K)  | Supplementary Information
Articles Top
Genome-wide genetic association of complex traits in heterogeneous stock mice pp879 - 887
William Valdar, Leah C Solberg, Dominique Gauguier, Stephanie Burnett, Paul Klenerman, William O Cookson, Martin S Taylor, J Nicholas P Rawlins, Richard Mott & Jonathan Flint
Published online: 09 July 2006 | doi:10.1038/ng1840
Abstract | Full text | PDF (361K)  | Supplementary Information
See also: News and Views by Darvasi
Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice pp888 - 895
Pengyuan Liu, Yian Wang, Haris Vikis, Anna Maciag, Daolong Wang, Yan Lu, Yan Liu & Ming You
Published online: 23 July 2006 | doi:10.1038/ng1849
Abstract | Full text | PDF (657K)  | Supplementary Information
Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways pp896 - 903
Ben Lehner, Catriona Crombie, Julia Tischler, Angelo Fortunato & Andrew G Fraser
Published online: 16 July 2006 | doi:10.1038/ng1844
Abstract | Full text | PDF (301K)  | Supplementary Information
See also: News and Views by Bussey et al.
Principal components analysis corrects for stratification in genome-wide association studies pp904 - 909
Alkes L Price, Nick J Patterson, Robert M Plenge, Michael E Weinblatt, Nancy A Shadick & David Reich
Published online: 23 July 2006 | doi:10.1038/ng1847
Abstract | Full text | PDF (199K)  | Supplementary Information
Mutations in genes encoding ribonuclease H2 subunits cause Aicardi-Goutières syndrome and mimic congenital viral brain infection pp910 - 916
Yanick J Crow, Andrea Leitch, Bruce E Hayward, Anna Garner, Rekha Parmar, Elen Griffith, Manir Ali, Colin Semple, Jean Aicardi, Riyana Babul-Hirji, Clarisse Baumann, Peter Baxter, Enrico Bertini, Kate E Chandler, David Chitayat, Daniel Cau, Catherine Déry, Elisa Fazzi, Cyril Goizet, Mary D King, Joerg Klepper, Didier Lacombe, Giovanni Lanzi, Hermione Lyall, María Luisa Martínez-Frías, Michèle Mathieu, Carole McKeown, Anne Monier, Yvette Oade, Oliver W Quarrell, Christopher D Rittey, R Curtis Rogers, Amparo Sanchis, John B P Stephenson, Uta Tacke, Marianne Till, John L Tolmie, Pam Tomlin, Thomas Voit, Bernhard Weschke, C Geoffrey Woods, Pierre Lebon, David T Bonthron, Chris P Ponting & Andrew P Jackson
Published online: 16 July 2006 | doi:10.1038/ng1842
Abstract | Full text | PDF (383K)  | Supplementary Information
See also: News and Views by Alarcón-Riquelme
Letters Top
Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locus pp917 - 920
Yanick J Crow, Bruce E Hayward, Rekha Parmar, Peter Robins, Andrea Leitch, Manir Ali, Deborah N Black, Hans van Bokhoven, Han G Brunner, Ben C Hamel, Peter C Corry, Frances M Cowan, Suzanne G Frints, Joerg Klepper, John H Livingston, Sally Ann Lynch, Roger F Massey, Jean François Meritet, Jacques L Michaud, Gerard Ponsot, Thomas Voit, Pierre Lebon, David T Bonthron, Andrew P Jackson, Deborah E Barnes & Tomas Lindahl
Published online: 16 July 2006 | doi:10.1038/ng1845
Abstract | Full text | PDF (176K)  | Supplementary Information
See also: News and Views by Alarcón-Riquelme
A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population pp921 - 925
Kouichi Ozaki, Hiroshi Sato, Aritoshi Iida, Hiroya Mizuno, Takahiro Nakamura, Yoshinari Miyamoto, Atsushi Takahashi, Tatsuhiko Tsunoda, Shiro Ikegawa, Naoyuki Kamatani, Masatsugu Hori, Yusuke Nakamura & Toshihiro Tanaka
Published online: 16 July 2006 | doi:10.1038/ng1846
Abstract | Full text | PDF (191K)  | Supplementary Information
A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice pp926 - 930
Minh D To, Jesus Perez-Losada, Jian-Hua Mao, Jeff Hsu, Tyler Jacks & Allan Balmain
Published online: 02 July 2006 | doi:10.1038/ng1836
Abstract | Full text | PDF (188K)  | Supplementary Information
See also: News and Views by Hunter
Probing long-distance regulatory interactions in the Drosophila melanogaster bithorax complex using Dam identification pp931 - 935
Fabienne Cléard, Yuri Moshkin, François Karch & Robert K Maeda
Published online: 02 July 2006 | doi:10.1038/ng1833
Abstract | Full text | PDF (182K)  | Supplementary Information
RNA interference machinery influences the nuclear organization of a chromatin insulator pp936 - 941
Elissa P Lei & Victor G Corces
Published online: 23 July 2006 | doi:10.1038/ng1850
Abstract | Full text | PDF (497K)  | Supplementary Information
The genetic basis for differences in leaf form between Arabidopsis thaliana and its wild relative Cardamine hirsuta pp942 - 947
Angela Hay & Miltos Tsiantis
Published online: 02 July 2006 | doi:10.1038/ng1835
Abstract | Full text | PDF (637K)  | Supplementary Information
See also: News and Views by Kellogg
A naturally occurring epigenetic mutation in a gene encoding an SBP-box transcription factor inhibits tomato fruit ripening pp948 - 952
Kenneth Manning, Mahmut Tör, Mervin Poole, Yiguo Hong, Andrew J Thompson, Graham J King, James J Giovannoni & Graham B Seymour
Published online: 09 July 2006 | doi:10.1038/ng1841
Abstract | Full text | PDF (360K)  | Supplementary Information
Emergence of a new disease as a result of interspecific virulence gene transfer pp953 - 956
Timothy L Friesen, Eva H Stukenbrock, Zhaohui Liu, Steven Meinhardt, Hua Ling, Justin D Faris, Jack B Rasmussen, Peter S Solomon, Bruce A McDonald & Richard P Oliver
Published online: 09 July 2006 | doi:10.1038/ng1839
Abstract | Full text | PDF (260K)  | Supplementary Information
Erratum Top
Erratum: Identification of the gene responsible for methylmalonic aciduria and homocystinuria, cblC type p957
Jordan P Lerner-Ellis, Jamie C Tirone, Peter D Pawelek, Carole Doré, Janet L Atkinson, David Watkins, Chantal F Morel, T Mary Fujiwara, Emily Moras, Angela R Hosack, Gail V Dunbar, Hana Antonicka, Vince Forgetta, C Melissa Dobson, Daniel Leclerc, Roy A Gravel, Eric A Shoubridge, James W Coulton, Pierre Lepage, Johanna M Rommens, Kenneth Morgan & David S Rosenblatt
doi:10.1038/ng0806-957a
Full text | PDF (59K)
Corrigendum Top
Corrigendum: PLA2G6, encoding a phospholipase A2, is mutated in neurodegenerative disorders with high brain iron p957
Neil V Morgan, Shawn K Westaway, Jenny E V Morton, Allison Gregory, Paul Gissen, Scott Sonek, Hakan Cangul, Jason Coryell, Natalie Canham, Nardo Nardocci, Giovanna Zorzi, Shanaz Pasha, Diana Rodriguez, Isabelle Desguerre, Amar Mubaidin, Enrico Bertini, Richard C Trembath, Alessandro Simonati, Carolyn Schanen, Colin A Johnson, Barbara Levinson, C Geoffrey Woods, Beth Wilmot, Patricia Kramer, Jane Gitschier, Eamonn R Maher & Susan J Hayflick
doi:10.1038/ng0806-957b
Full text | PDF (61K)
  Top
 
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Nature Genetics
ISSN: 1061-4036
EISSN: 1546-1718
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