A new study involving a population of 1,904 heterogeneous mice bred for 50 generations, phenotyped for 101 traits and genotyped for 13,459 SNPs, presents the most comprehensive analysis thus far of complex traits in mice. The work represents a landmark resource for the mouse genetics community and offers important insights into the genetic architecture of complex traits.
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References
- 1.
Valdar, W. et al. Nat. Genet. 38, 879–887 (2006).
- 2.
Darvasi, A. & Soller, M. Genetics 141, 1199–1207 (1995).
- 3.
Couzin, J. Science 309, 81 (2005).
- 4.
Weiss, K.M. & Terwilliger, J.D. Nat. Genet. 26, 151–157 (2000).
- 5.
Flint, J., Valdar, W., Shifman, S. & Mott, R. Nat. Rev. Genet. 6, 271–286 (2005).
- 6.
Austin, C.P. et al. Nat. Genet. 36, 921–924 (2004).
- 7.
Auwerx, J. et al. Nat. Genet. 36, 925–927 (2004).
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Affiliations
Ariel Darvasi is in the Department of Genetics, The Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem 91904, Israel. arield@cc.huji.ac.il
- Ariel Darvasi
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Further reading
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1.
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