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Nature Genetics 38, 652–658 (1 June 2006) |
doi:10.1038/ng1808
A common variant associated with prostate cancer in European and African populations
Laufey T Amundadottir
,
Patrick Sulem
,
Julius Gudmundsson
,
Agnar Helgason
,
Adam Baker
,
Bjarni A Agnarsson
,
Asgeir Sigurdsson
,
Kristrun R Benediktsdottir
,
Jean-Baptiste Cazier
,
Jesus Sainz
,
Margret Jakobsdottir
,
Jelena Kostic
,
Droplaug N Magnusdottir
,
Shyamali Ghosh
,
Kari Agnarsson
,
Birgitta Birgisdottir
,
Louise Le Roux
,
Adalheidur Olafsdottir
,
Thorarinn Blondal
,
Margret Andresdottir
,
Olafia Svandis Gretarsdottir
,
Jon T Bergthorsson
,
Daniel Gudbjartsson
,
Arnaldur Gylfason
,
Gudmar Thorleifsson
,
Andrei Manolescu
,
Kristleifur Kristjansson
,
Gudmundur Geirsson
,
Helgi Isaksson
,
Julie Douglas
,
Jan-Erik Johansson
,
Katarina B|[auml]|lter
,
Fredrik Wiklund
,
James E Montie
,
Xiaoying Yu
,
Brian K Suarez
,
Carole Ober
,
Kathleen A Cooney
,
Henrik Gronberg
,
William J Catalona
,
Gudmundur V Einarsson
,
Rosa B Barkardottir
,
Jeffrey R Gulcher
,
Augustine Kong
,
Unnur Thorsteinsdottir
&
Kari Stefansson
Abstract
With the increasing incidence of prostate cancer, identifying common genetic variants that confer risk of the disease is important. Here we report such a variant on chromosome 8q24, a region initially identified through a study of Icelandic families.
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