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Published online 3 October 2007 | Nature 449, 515 (2007) | doi:10.1038/449515a
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Minimum telomere length defined for healthy cells
Mechanism for chromosome corruption also revealed.
How long have I got left, doctor? For a cell, at least, scientists may be close to an answer. A cell's lifespan depends on the length of its telomeres — the regions of repeating DNA that protect the ends of chromosomes.
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What should be the minimum percent of microhomology needed for the end joining of two chromosomes ? What the Spectral Karyotyping (SKY) analysis revealed ?