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| Nature Neuroscience presents a special focus on childhood developmental disorders, which contains four perspectives exploring the overlap between normal and abnormal development, as well as the commonalties between different disorders. Disorders covered include autism, specific language impairment, dyslexia, and the mental retardation syndrome fragile X. Thanks to generous support from our sponsors, the March of Dimes, Autism Speaks and Cure Autism Now, this focus will be freely available online through December 2006. |
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| Editorial | Top |
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Fighting animal rights terrorism p1195 doi:10.1038/nn1006-1195 Abstract | Full text | PDF
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| Book Review | Top |
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Autism at the crossroads: determining the phenotype matters for neuroscience p1197 Reviewed by: Tony Charman doi:10.1038/nn1006-1197 Full text | PDF
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| News and Views | Top |
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Keeping the memories flowing pp1199 - 1200 Gregory J Quirk & Ivan Vidal-Gonzalez doi:10.1038/nn1006-1199 Abstract | Full text | PDF
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Turning by asymmetric actin pp1201 - 1203 Guo-li Ming doi:10.1038/nn1006-1201 Abstract | Full text | PDF
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See also: Article by Leung et al. | Article by Yao et al. |
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Hooking up new synapses pp1203 - 1204 Thomas Biederer doi:10.1038/nn1006-1203 Abstract | Full text | PDF
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Intercellular miscommunication in polyglutamine pathogenesis pp1205 - 1206 Christopher A Ross & Don W Cleveland doi:10.1038/nn1006-1205 Abstract | Full text | PDF
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Walk the line: parietal neurons respect category boundaries pp1207 - 1208 Vincent P Ferrera & Jack Grinband doi:10.1038/nn1006-1207 Abstract | Full text | PDF
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| Introduction | Top |
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Focus on Childhood Developmental Disorders Childhood developmental disorders p1209 Charvy Narain doi:10.1038/nn1006-1209 Full text | PDF
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| Sponsor's Foreword | Top |
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Focus on Childhood Developmental Disorders A genetics pioneer focused on child health challenges p1211 Michael Katz doi:10.1038/nn1006-1211 Full text | PDF
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| Perspectives | Top |
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Focus on Childhood Developmental Disorders From genes to behavior in developmental dyslexia pp1213 - 1217 Albert M Galaburda, Joseph LoTurco, Franck Ramus, R Holly Fitch & Glenn D Rosen Published online: 26 September 2006 | doi:10.1038/nn1772 Abstract | Full text | PDF
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Focus on Childhood Developmental Disorders Time to give up on a single explanation for autism pp1218 - 1220 Francesca Happé, Angelica Ronald & Robert Plomin Published online: 26 September 2006 | doi:10.1038/nn1770 Abstract | Full text | PDF
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Focus on Childhood Developmental Disorders Fragile X syndrome and autism at the intersection of genetic and neural networks pp1221 - 1225 Matthew K Belmonte & Thomas Bourgeron Published online: 26 September 2006 | doi:10.1038/nn1765 Abstract | Full text | PDF
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Focus on Childhood Developmental Disorders What developmental disorders can tell us about the nature and origins of language pp1226 - 1229 Gary Marcus & Hugh Rabagliati Published online: 26 September 2006 | doi:10.1038/nn1766 Abstract | Full text | PDF
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| Brief Communications | Top |
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Kinase activity of mutant LRRK2 mediates neuronal toxicity pp1231 - 1233 Wanli W Smith, Zhong Pei, Haibing Jiang, Valina L Dawson, Ted M Dawson & Christopher A Ross Published online: 17 September 2006 | doi:10.1038/nn1776 Abstract | Full text | PDF
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Local caspase activity directs engulfment of dendrites during pruning pp1234 - 1236 Darren W Williams, Shu Kondo, Agnieszka Krzyzanowska, Yasushi Hiromi & James W Truman Published online: 17 September 2006 | doi:10.1038/nn1774 Abstract | Full text | PDF
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NMDA receptors are critical for unleashing consolidated auditory fear memories pp1237 - 1239 Cyrinne Ben Mamou, Karine Gamache & Karim Nader Published online: 24 September 2006 | doi:10.1038/nn1778 Abstract | Full text | PDF
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Brain state and contrast sensitivity in the awake visual thalamus pp1240 - 1242 Monica Cano, Tatiana Bezdudnaya, Harvey A Swadlow & Jose-Manuel Alonso Published online: 10 September 2006 | doi:10.1038/nn1760 Abstract | Full text | PDF
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When sustained attention impairs perception pp1243 - 1245 Sam Ling & Marisa Carrasco Published online: 10 September 2006 | doi:10.1038/nn1761 Abstract | Full text | PDF
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| Articles | Top |
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Asymmetrical -actin mRNA translation in growth cones mediates attractive turning to netrin-1 pp1247 - 1256 Kin-Mei Leung, Francisca PG van Horck, Andrew C Lin, Rachel Allison, Nancy Standart & Christine E Holt Published online: 17 September 2006 | doi:10.1038/nn1775 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Ming | Article by Yao et al. |
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Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones pp1257 - 1264 Karen Y Wu, Jonathan H Zippin, David R Huron, Margarita Kamenetsky, Ulrich Hengst, Jochen Buck, Lonny R Levin & Samie R Jaffrey Published online: 10 September 2006 | doi:10.1038/nn1767 Abstract | Full text | PDF
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An essential role for -actin mRNA localization and translation in Ca2+-dependent growth cone guidance pp1265 - 1273 Jiaqi Yao, Yukio Sasaki, Zhexing Wen, Gary J Bassell & James Q Zheng Published online: 17 September 2006 | doi:10.1038/nn1773 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Ming | Article by Leung et al. |
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Focal adhesion kinase signaling at sites of integrin-mediated adhesion controls axon pathfinding pp1274 - 1283 Estuardo Robles & Timothy M Gomez Published online: 03 September 2006 | doi:10.1038/nn1762 Abstract | Full text | PDF
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Meninges control tangential migration of hem-derived Cajal-Retzius cells via CXCL12/CXCR4 signaling pp1284 - 1293 Víctor Borrell & Oscar Marín Published online: 10 September 2006 | doi:10.1038/nn1764 Abstract | Full text | PDF
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NGL family PSD-95–interacting adhesion molecules regulate excitatory synapse formation pp1294 - 1301 Seho Kim, Alain Burette, Hye Sun Chung, Seok-Kyu Kwon, Jooyeon Woo, Hyun Woo Lee, Karam Kim, Hyun Kim, Richard J Weinberg & Eunjoon Kim Published online: 17 September 2006 | doi:10.1038/nn1763 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Biederer |
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Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport pp1302 - 1311 Sara K Custer, Gwenn A Garden, Nishi Gill, Udo Rueb, Randell T Libby, Christian Schultz, Stephan J Guyenet, Thomas Deller, Lesnick E Westrum, Bryce L Sopher & Albert R La Spada Published online: 27 August 2006 | doi:10.1038/nn1750 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Ross & Cleveland |
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Nonlinear, binocular interactions underlying flow field selectivity of a motion-sensitive neuron pp1312 - 1320 Karl Farrow, Juergen Haag & Alexander Borst Published online: 10 September 2006 | doi:10.1038/nn1769 Abstract | Full text | PDF
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Emotional enhancement of memory via amygdala-driven facilitation of rhinal interactions pp1321 - 1329 Rony Paz, Joe Guillaume Pelletier, Elizabeth P Bauer & Denis Paré Published online: 10 September 2006 | doi:10.1038/nn1771 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Quirk & Vidal-Gonzalez |
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Functional alignment of feedback effects from visual cortex to thalamus pp1330 - 1336 Wei Wang, Helen E Jones, Ian M Andolina, Thomas E Salt & Adam M Sillito Published online: 17 September 2006 | doi:10.1038/nn1768 Abstract | Full text | PDF
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A human parietal face area contains aligned head-centered visual and tactile maps pp1337 - 1343 Martin I Sereno & Ruey-Song Huang Published online: 24 September 2006 | doi:10.1038/nn1777 Abstract | Full text | PDF
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