Chronic cocaine exposure induces long-lasting, transcription-dependent changes in neuronal function. A genome-wide sequencing study shows how cocaine changes the epigenome to exert specific, long-lasting effects on neuronal transcription.
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References
Feng, J. et al. Nat. Neurosci. 18, 536–544 (2015).
Lister, R. et al. Science 341, 1237905 (2013).
Kriaucionis, S. & Heintz, N. Science 324, 929–930 (2009).
Tahiliani, M. et al. Science 324, 930–935 (2009).
Koh, K.P. et al. Cell Stem Cell 8, 200–213 (2011).
Ito, S. et al. Nature 466, 1129–1133 (2010).
Dawlaty, M.M. et al. Dev. Cell 24, 310–323 (2013).
Szulwach, K.E. et al. Nat. Neurosci. 14, 1607–1616 (2011).
Rudenko, A. et al. Neuron 79, 1109–1122 (2013).
Li, X. et al. Proc. Natl. Acad. Sci. USA 111, 7120–7125 (2014).
Kaas, G.A. et al. Neuron 79, 1086–1093 (2013).
Wen, L. et al. Genome Biol. 15, R49 (2014).
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West, A. Cocaine shapes chromatin landscapes via Tet1. Nat Neurosci 18, 478–480 (2015). https://doi.org/10.1038/nn.3985
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DOI: https://doi.org/10.1038/nn.3985