A study finds that, during movement preparation, when motor cortex is active, but elicits no muscle output, firing of individual neurons in dorsal premotor and primary motor cortex cancels out at the level of population activity.
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References
Kaufman, M.T., Churchland, M.M., Ryu, S.I. & Shenoy, K.V. Nat. Neurosci. 17, 440–448 (2014).
Hétu, S. et al. Neurosci. Biobehav. Rev. 37, 930–949 (2013).
Bremner, L.R. & Andersen, R.A. Neuron 75, 342–351 (2012)
Buch, E.R., Brasted, P.J. & Wise, S.P. Exp. Brain Res. 169, 69–84 (2006).
Rizzolatti, G. & Sinigaglia, C. Nat. Rev. Neurosci. 11, 264–274 (2010).
Vigneswaran, G., Philipp, R., Lemon, R.N. & Kraskov, A. Curr. Biol. 23, 236–243 (2013).
Hishikawa, Y. & Shimizu, T. Adv. Neurol. 67, 245–271 (1995).
Evinger, C., Kanako, C.R. & Fuchs, A.F. J. Neurophysiol. 47, 827–844 (1982).
Kaufman, M.T. et al. J. Neurophysiol. 104, 799–810 (2010).
Kaufman, M.T., Churchland, M.M. & Shenoy, K.V. J. Neurophysiol. 110, 817–825 (2013).
Cohen, O., Sherman, E., Zinger, N., Perlmutter, S. & Prut, Y. Curr. Opin. Neurobiol. 20, 696–703 (2010).
Afshar, A. et al. Neuron 71, 555–564 (2011).
Scholz, J.P. & Schöner, G. Exp. Brain Res. 126, 289–306 (1999).
Georgopoulos, A.P., Kettner, R.E. & Schwartz, A.B. J. Neurosci. 8, 2928–2937 (2008).
Partridge, L.D. Am. J. Physiol. 242, R172–R177 (1982).
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Sanger, T., Kalaska, J. Crouching tiger, hidden dimensions. Nat Neurosci 17, 338–340 (2014). https://doi.org/10.1038/nn.3663
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DOI: https://doi.org/10.1038/nn.3663
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