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Seawater is the most abundant water source for hydrogen fuel production. Here the authors report a binary photoelectrode of Pt catalyst-GaN semiconductor with promising efficiency, productivity, and stability for seawater hydrogen evolution.
Direct hydrogen peroxide electrosynthesis offers a sustainable alternative to the traditional energy-intensive anthraquinone technology. Here, the authors report a scalable cobalt single-site catalyst for hydrogen peroxide synthesis at industrial-relevant currents in acidic, neutral or alkaline electrolyte.
Polyacetylenes are an important class of conjugated polymers but are generally synthesized via metal-catalyzed coordination polymerization leaving trace metals as impurities. Here the authors demonstrate a free radical polymerization of co-crystalized acetylene monomers without the need of a metal catalyst.
Non-specific phospholipase C (NPC) is a plant-specific phospholipid-hydrolyzing enzyme. Here, the authors define the molecular basis of how Arabidopsis NPC works, and provide new mechanistic insights into the members of phospholipase family.
Frequency-bin qubits get the best of time-bin and dual-rail encodings, but require external modulators and pulse shapers to build arbitrary states. Here, instead, the authors work directly on-chip by controlling the interference of biphoton amplitudes generated in multiple, coherently-pumped ring resonators.
Accurate measurement of defect structures is hindered by complex atomic configuration and/or crystal tilt. Here, the authors realize sub-nanometer mapping of crystal tilt and deep-subangstrom resolution and depth-dependent imaging of dislocations.
The genetic determinants of long-distance migration in birds are largely unknown. Sokolovskis et al. tracked genotyped hybrid willow warblers from a migratory divide in Sweden and find that autumn migration direction is consistent with a dominant inheritance pattern of two large effect loci that interact through epistasis.
It remains unclear how the Stroop effect occurs and gets resolved in the human brain. Here, the authors show that a functional loop involving the prefrontal cortex and cerebellum may play a critical role during word-color perception.
RBR E3 ubiquitin ligases utilise a 2-step catalytic mechanism previously defined for only few of the RBR family members. Here, the authors examine the poorly studied RBRs HOIL-1 and RNF216 to define general principles of RBR catalysis and regulation and identify specific functional differences.
Conformational heterogeneity is key to understand how macromolecular function and structure converge. Here, the authors propose an algorithm designed to estimate structural landscapes directly from Cryo-EM particle images.
Self-assembly processes usually yield symmetric compounds. Here, the authors report the distortion of a symmetric hydrogen-bonded resorcin[4]arene cage upon encapsulation of an iridium complex.
The recently described protein HAPSTR1 governs cellular stress resilience. Here, the authors discover a mammalian HAPSTR1 paralog, called HAPSTR2, which formed via retro-transposition and operates to augment and buffer cellular stress signaling.
The nature of the superconductivity in the kagome metals AV3Sb5 (A = K, Rb, Cs) remains under debate. Here, using muon spin spectroscopy, the authors find that the superconductivity in RbV3Sb5 and KV3Sb5 evolves from nodal to nodeless with increasing pressure and the superconducting state breaks time-reversal symmetry after suppression of the charge order.
Feedback control applied to mechanical resonators can lead to the formation of various complex dynamic behaviors. Here the authors demonstrate flexible and controllable switching between dynamical structures in the response of harmonically driven micro-mechanical resonators.
Cellular senescence and associated secretory phenotype (SASP) are thought to contribute to aging and tissue dysfunction, though it is unclear how SASP impacts regeneration. Here the authors show that SASP factors impair regeneration, and that Ptk7 is a key secreted protein mediating that dysregulation.
Here the authors establish the SPOC domain as a universal reader of the RNA Pol II CTD code and a versatile reader of phosphoserine marks found in co- and post-transcriptional regulators such as m6A writer and reader proteins.
Regulation of oriented cell divisions during development is important to position daughter cells and build a structured and functional tissue. Here the authors show that Annexin A1 is a key polarity protein that regulates planar orientation of the cell division axis to guide mammary epithelial morphogenesis.
Age-related osteoporosis is known to be dependent on TGFβ1 signalling. Here the authors show that a subset of neutrophils (identified by TGFβ1+CCR5+) increase during aging in mouse bone marrow resulting in bone loss, while a CCR5 antagonist can reduce the neutrophil numbers and increase bone mass in aged mice.
Soft robotics holds promise for realizing easy control over complex locomotion and deformation. Lin et al. report an earthworm-inspired untethered magnetic robot that consists one-piece-mold folded diaphragm to achieve large three-dimensional deformation with inside-volume change capability.