Browse Articles

  • Article | | open

    Chromosomal rearrangements are key events in the pathogenesis of a range of disorders. Here the authors utilize a zinc finger nuclease translocation reporter to identify PARP3 as a regulator of these events at sites enriched for G quadruplex DNA.

    • Tovah A. Day
    • , Jacob V. Layer
    • , J. Patrick Cleary
    • , Srijoy Guha
    • , Kristen E. Stevenson
    • , Trevor Tivey
    • , Sunhee Kim
    • , Anna C. Schinzel
    • , Francesca Izzo
    • , John Doench
    • , David E. Root
    • , William C. Hahn
    • , Brendan D. Price
    •  & David M. Weinstock
  • Article | | open

    Wearable electronics have been utilized for a number of applications including for ocular use, although their use has been limited to a single function. Here, the authors developed a multifunctional contact lens with wireless electronics for measurement of glucose and intraocular pressure.

    • Joohee Kim
    • , Minji Kim
    • , Mi-Sun Lee
    • , Kukjoo Kim
    • , Sangyoon Ji
    • , Yun-Tae Kim
    • , Jihun Park
    • , Kyungmin Na
    • , Kwi-Hyun Bae
    • , Hong Kyun Kim
    • , Franklin Bien
    • , Chang Young Lee
    •  & Jang-Ung Park
  • Article | | open

    Genetic variants at multiple loci of chr5p15.33 have been associated with susceptibility to numerous cancers. Here the authors show that the association of one of these loci may be explained by a variant, rs36115365, influencing telomerase reverse transcriptase (TERT) expression via ZNF148.

    • Jun Fang
    • , Jinping Jia
    • , Matthew Makowski
    • , Mai Xu
    • , Zhaoming Wang
    • , Tongwu Zhang
    • , Jason W. Hoskins
    • , Jiyeon Choi
    • , Younghun Han
    • , Mingfeng Zhang
    • , Janelle Thomas
    • , Michael Kovacs
    • , Irene Collins
    • , Marta Dzyadyk
    • , Abbey Thompson
    • , Maura O’Neill
    • , Sudipto Das
    • , Qi Lan
    • , Roelof Koster
    • , PanScan Consortium
    • , Federico Canzian
    • , Charles Kooperberg
    • , Zhaoming Wang
    • , Alan A Arslan
    • , Paige M Bracci
    • , Julie Buring
    • , Eric J Duell
    • , Steven Gallinger
    • , Eric J Jacobs
    • , Aruna Kamineni
    • , Stephen Van Den Eeden
    • , Alison P Klein
    • , Laurence N Kolonel
    • , Donghui Li
    • , Sara H Olson
    • , Harvey A Risch
    • , Howard D Sesso
    • , Kala Visvanathan
    • , Wei Zheng
    • , Demetrius Albanes
    • , Melissa A Austin
    • , Marie-Christine Boutron-Ruault
    • , H Bas Bueno-de-Mesquita
    • , Michelle Cotterchio
    • , J Michael Gaziano
    • , Edward L Giovannucci
    • , Michael Goggins
    • , Myron Gross
    • , Manal Hassan
    • , Kathy J Helzlsouer
    • , Elizabeth A Holly
    • , David J Hunter
    • , Mazda Jenab
    • , Rudolf Kaaks
    • , Timothy J Key
    • , Kay-Tee Khaw
    • , Vittorio Krogh
    • , Robert C Kurtz
    • , Andrea LaCroix
    • , Loic Le Marchand
    • , Satu Mannisto
    • , Alpa V Patel
    • , Petra H M Peeters
    • , Elio Riboli
    • , Xiao-Ou Shu
    • , Malin Sund
    • , Mark Thornquist
    • , Anne Tjønneland
    • , Geoffrey S Tobias
    • , Dimitrios Trichopoulos
    • , Jean Wactawski-Wende
    • , Herbert Yu
    • , Kai Yu
    • , Anne Zeleniuch-Jacquotte
    • , Robert Hoover
    • , Patricia Hartge
    • , Charles Fuchs
    • , Stephen J Chanock
    • , TRICL Consortium
    • , Victoria Stevens
    • , Demetrios Albanes
    • , Neil E Caporaso
    • , Paul Brennan
    • , James McKay
    • , Xifeng Wu
    • , Rayjean J Hung
    • , John R McLaughlin
    • , Heike Bickeboller
    • , Angela Risch
    • , Erich Wichmann
    • , Richard Houlston
    • , GenoMEL Consortium
    • , Graham Mann
    • , John Hopper
    • , Joanne Aitken
    • , Bruce Armstrong
    • , Graham Giles
    • , Elizabeth Holland
    • , Richard Kefford
    • , Anne Cust
    • , Jennifer H. Barrett
    • , Amaury Vaysse
    • , Coby Out
    • , Susana Puig
    • , Miriam Potrony
    • , Wilma Bergman
    • , Tadeusz Debniak
    • , Mark M. Iles
    • , Pascal W. T. C. Jansen
    • , Cristina Carrera
    • , Alisa M Goldstein
    • , Valerie Chaudru
    • , Marie-Francoise Avril
    • , Luc Thomas
    • , Veronica Hoiom
    • , Marinus van Praag
    • , Giorgi Landi
    • , Stuart Mac Gregor
    • , Nelleke Gruis
    • , Gemma Tell Marti
    • , Myriam Bossard
    • , Josep Malvehy
    • , Fabio Arcangeli
    • , Patricia Jeannin
    • , Christopher I. Amos
    • , Hans Vasen
    • , Grant Montgomery
    • , Mark Harland
    • , Florence Demenais
    • , Christian Ingvar
    • , Montse Mila
    • , Eva Wierzbicka
    • , Dominique Leroux
    • , Jeremie Nsengimana
    • , John Davies
    • , Lars A Akslen
    • , Virginia Andreotti
    • , Jo Gascoyne
    • , Bart Janssen
    • , Alon Scope
    • , Joan-AntonPuig Batille
    • , Srdjan Novakovic
    • , Brian M. Wolpin
    • , Jon Laye
    • , Peter Kraft
    • , Francoise Boitier
    • , Goran Jonsson
    • , Dyon Snels
    • , Hakan Olsson
    • , Nandita Mitra
    • , Paola Queirolo
    • , David Whiteman
    • , Sara Olson
    • , Bert Bakker
    • , Lorenze Pastorino
    • , Caroline Robert
    • , Juliette Randerson-Moor
    • , Celia Badenas
    • , Ake Borg
    • , William Bruno
    • , Marko Hocevar
    • , Katherine A. McGlynn
    • , Esther Azizi
    • , Ludovic Martin
    • , May Chan
    • , Thorkell Andresson
    • , Fabienne Lesueur
    • , Stephane Dalle
    • , Frederic Caux
    • , Jan Lubinski
    • , Irit Cohen-Manheim
    • , Han van der Rhee
    • , Julie Lang
    • , Eitan Freidman
    • , David Elder
    • , Per Helsing
    • , Eve Maubec
    • , Johan Hansson
    • , Orna Baron-Epel
    • , Barbara Peric
    • , Maria Teresa Landi
    • , Laufey T. Amundadottir
    • , Francesco Spagnolo
    • , Lieve Brochez
    • , Paula Aguilera
    • , Marianne Crijns
    • , Kari Nielsen
    • , Per Arne Andresen
    • , Kevin M. Brown
    • , Rianne Gerritsen
    • , Oliver Caron
    • , Dominique Stoppa-Lyonnet
    • , Rachael S. Stolzenberg-Solomon
    • , Peter A. Kanetsky
    • , Gloria M. Petersen
    • , Marcel Bekkenk
    • , Oliviier Dereure
    • , Petra Skerl
    • , Helen Schmid
    • , Julia A. Newton-Bishop
    • , Michiel Vermeulen
    • , Jan Nico Bouwes Bavinck
    • , Nicholas Martin
    • , Margaret A Tucker
    • , Hamida Mohamdi
    • , Christine Mateus
    • , Anita Schmidt Zander
    • , Nick Hayward
    • , Pablo Iglesias-Garcia
    • , Sally O'Shea
    • , Yael Laitman
    • , John C. Taylor
    • , David Duffy
    • , Alicia Barreiro
    • , Pol Gimenez Xavier
    • , Frans A van Nieuwpoort
    • , Pier Alberto Bertazzi
    • , Donato Calista
    • , Katherine L. Nathanson
    • , Xiaohong R Yang
    • , Rona Mackie
    • , Felix Pavlotsky
    • , Alison M. Dunning
    • , Paola Ghiorzo
    • , Ramon Pigem
    • , Nilanjan Chatterjee
    • , Daniel Gabriel
    • , D. Timothy Bishop
    • , Anders Molvern
    • , Mark Jenkins
    • , Paola Minghetti
    • , Brigitte Bressac-de Paillerets
    • , Michael Ming
    • , Jeanet ter Huurne
    • , Helge Rootwelt
    • , Nienke van der Stoep
    • , Nicole Kukutsch
    • , Giovanna Bianchi Scarra
    •  & Katja Harbst
  • Article | | open

    The mechanistic coupling of cell growth and cell cycle control with cell size regulation in tissues is not well understood. Here, the authors show that within the shoot apical meristem of Arabidopsis cell size depends on developmental stage, genotype and environmental signals; however cell growth and cell division are cell-autonomously coordinated.

    • Angharad R. Jones
    • , Manuel Forero-Vargas
    • , Simon P. Withers
    • , Richard S. Smith
    • , Jan Traas
    • , Walter Dewitte
    •  & James A. H. Murray
  • Article | | open

    Emulsions are mixtures of liquids which have applications to pharmaceutical, cosmetic and food components. Here Tcholakova et al. have developed a low-energy emulsification method which requires a low amount of surfactant, works for temperature-sensitive compounds and has potential for scale-up.

    • Slavka Tcholakova
    • , Zhulieta Valkova
    • , Diana Cholakova
    • , Zahari Vinarov
    • , Ivan Lesov
    • , Nikolai Denkov
    •  & Stoyan K. Smoukov
  • Article | | open

    Asymmetric nuclear positioning in the fruit fly oocyte is essential for the correct localization of axis determinants. Here, the authors show that different microtubule-dependent mechanisms contribute to nuclear transport and ensure the robustness of nuclear positioning.

    • Nicolas Tissot
    • , Jean-Antoine Lepesant
    • , Fred Bernard
    • , Kevin Legent
    • , Floris Bosveld
    • , Charlotte Martin
    • , Orestis Faklaris
    • , Yohanns Bellaïche
    • , Maïté Coppey
    •  & Antoine Guichet
  • Article | | open

    Primary dysmenorrhoea, the most common gynaecologic complaint, remains genetically and pathophysiologically elusive. Here, Li and colleagues identify common variants in ZMIZ1 and near NGF conferring risk for primary dysmenorrhoea using genome-wide association study in a Chinese population.

    • Zhiqiang Li
    • , Jianhua Chen
    • , Ying Zhao
    • , Yujiong Wang
    • , Jinrui Xu
    • , Jue Ji
    • , Jingyi Shen
    • , Weiping Zhang
    • , Zuosong Chen
    • , Qilin Sun
    • , Lijuan Mao
    • , Shulin Cheng
    • , Bo Yang
    • , Dongtao Zhang
    • , Yufeng Xu
    • , Yingying Zhao
    • , Danping Liu
    • , Yinhuan Shen
    • , Weijie Zhang
    • , Changgui Li
    • , Jiawei Shen
    •  & Yongyong Shi
  • Article | | open

    The functional significance of T-cell infiltration in pancreatic ductal adenocarcinoma in relation to desmoplastic stroma is unclear. Here the authors develop a method to spatially resolve tumour stroma composition and find that spatial T-cell infiltration correlates with patient prognosis regardless of desmoplasia.

    • Julienne L. Carstens
    • , Pedro Correa de Sampaio
    • , Dalu Yang
    • , Souptik Barua
    • , Huamin Wang
    • , Arvind Rao
    • , James P. Allison
    • , Valerie S. LeBleu
    •  & Raghu Kalluri
  • Article | | open

    Frontal eye field (FEF) is a visual prefrontal area involved in top-down attention. Here the authors report that FEF neurons projecting to V4/MT are persistently active during spatial working memory, and V4/MT neurons show changes in receptive field and gain at the location held in working memory.

    • Yaser Merrikhi
    • , Kelsey Clark
    • , Eddy Albarran
    • , Mohammadbagher Parsa
    • , Marc Zirnsak
    • , Tirin Moore
    •  & Behrad Noudoost
  • Article | | open

    Centrosome duplication is synchronized with cell cycle events but how this is regulated at a molecular level is unclear. Here, the authors show that the DNA replication licensing factor Cdc6 restrains centrosome duplication via binding and inhibiting Sas-6, and the inhibition of Cdc6 on Sas-6 is negatively regulated by Plk4 phosphorylation.

    • Xiaowei Xu
    • , Shijiao Huang
    • , Boyan Zhang
    • , Fan Huang
    • , Wangfei Chi
    • , Jingyan Fu
    • , Gang Wang
    • , Si Li
    • , Qing Jiang
    •  & Chuanmao Zhang
  • Article | | open

    Energetic liquids often suffer from low energy density. Here, the authors create a highly energetic liquid by stabilizing aluminium nanoparticles in ferritin liquid protein, and use this ink to print energetic 3D structures.

    • Joseph M. Slocik
    • , Ruel McKenzie
    • , Patrick B. Dennis
    •  & Rajesh R. Naik
  • Article | | open

    Electronegativity is a fundamental concept in chemistry; however it is an elusive quantity to evaluate experimentally. Here, the authors estimate the Pauling electronegativity of individual atoms on a surface via atomic force microscopy using a variety of chemically reactive tips.

    • Jo Onoda
    • , Martin Ondráček
    • , Pavel Jelínek
    •  & Yoshiaki Sugimoto
  • Article | | open

    As alkali-ion battery anodes, metal oxide nanomaterials suffer from severe structural degradation after charging/discharging cycling. Here the authors develop two-dimensional holey nanosheet anodes which display minimal structural changes during electrochemical operation.

    • Lele Peng
    • , Pan Xiong
    • , Lu Ma
    • , Yifei Yuan
    • , Yue Zhu
    • , Dahong Chen
    • , Xiangyi Luo
    • , Jun Lu
    • , Khalil Amine
    •  & Guihua Yu
  • Article | | open

    Unravelling the fundamental mechanisms of emergence of complex behaviour is key to understanding living systems. Here, the authors provide a simple experimental platform to investigate and control a rich set of complex phenomena, akin to those seen in living organisms, from a nonliving system of colloidal nanoparticles.

    • Serim Ilday
    • , Ghaith Makey
    • , Gursoy B. Akguc
    • , Özgün Yavuz
    • , Onur Tokel
    • , Ihor Pavlov
    • , Oguz Gülseren
    •  & F. Ömer Ilday
  • Article | | open

    Quantum communications will be used to transmit entanglement and secure keys, but it is important to estimate their optimal transfer rates. Here the authors compute the fundamental limit of repeaterless quantum communications for the most relevant practical scenario.

    • Stefano Pirandola
    • , Riccardo Laurenza
    • , Carlo Ottaviani
    •  & Leonardo Banchi
  • Article | | open

    Hyperpolarized magnetic resonance imaging can enhance imaging contrast by orders of magnitude, but applications are limited by the thermal relaxation of hyperpolarized states. Here, Waddington et al. demonstrate the on-demand hyperpolarization of hydrogen spins through the Overhauser effect with nanodiamonds.

    • David E. J. Waddington
    • , Mathieu Sarracanie
    • , Huiliang Zhang
    • , Najat Salameh
    • , David R. Glenn
    • , Ewa Rej
    • , Torsten Gaebel
    • , Thomas Boele
    • , Ronald L. Walsworth
    • , David J. Reilly
    •  & Matthew S. Rosen
  • Article | | open

    Japanese encephalitis virus (JEV) is a Flavivirus responsible for thousands of deaths every year for which there are no specific anti-virals. Here, Wang et al. report the cryo-EM structure of mature JEV at near-atomic resolution and identify structural elements that modulate stability and virulence.

    • Xiangxi Wang
    • , Shi-Hua Li
    • , Ling Zhu
    • , Qing-Gong Nian
    • , Shuai Yuan
    • , Qiang Gao
    • , Zhongyu Hu
    • , Qing Ye
    • , Xiao-Feng Li
    • , Dong-Yang Xie
    • , Neil Shaw
    • , Junzhi Wang
    • , Thomas S. Walter
    • , Juha T. Huiskonen
    • , Elizabeth E. Fry
    • , Cheng-Feng Qin
    • , David I. Stuart
    •  & Zihe Rao
  • Article | | open

    Aberrant activation of TGF-β signalling promotes cancer metastasis but the initial steps of this activation are unclear. Here Xie et al. show that FAF1 regulates the surface levels of TGF-β type II receptor thus influencing the persistence of the signalling and breast cancer metastasis.

    • Feng Xie
    • , Ke Jin
    • , Li Shao
    • , Yao Fan
    • , Yifei Tu
    • , Yihao Li
    • , Bin Yang
    • , Hans van Dam
    • , Peter ten Dijke
    • , Honglei Weng
    • , Steven Dooley
    • , Shuai Wang
    • , Junling Jia
    • , Jin Jin
    • , Fangfang Zhou
    •  & Long Zhang
  • Article | | open

    Silver compounds have long been known to possess exceptional solid-state conductivity. Here the authors present silver closo-boranes in which facile Ag+ migration occurs, leading to exceptionally high ion conductivities and potential utility in silver nanowire production and photocatalysis due to their semiconductivity.

    • Mark Paskevicius
    • , Bjarne R. S. Hansen
    • , Mathias Jørgensen
    • , Bo Richter
    •  & Torben R. Jensen
  • Article | | open

    Synthetic circuits in host cells compete with endogenous processes for limited resources. Here the authors use MazF to funnel cellular resources to a synthetic circuit to increase product production and demonstrate how resource allocation can be manipulated.

    • Ophelia S. Venturelli
    • , Mika Tei
    • , Stefan Bauer
    • , Leanne Jade G. Chan
    • , Christopher J. Petzold
    •  & Adam P Arkin
  • Article | | open

    The Hippo pathway has recently been implicated in Schwann cell (SC) development and myelination. Here the authors reveal mechanistic insights into how TAZ and YAP regulate and interact with target genes; they further identify a negative feedback loop between TAZ/YAP and G protein Gαs that balances SC proliferation and differentiation.

    • Yaqi Deng
    • , Lai Man Natalie Wu
    • , Shujun Bai
    • , Chuntao Zhao
    • , Haibo Wang
    • , Jincheng Wang
    • , Lingli Xu
    • , Masahide Sakabe
    • , Wenhao Zhou
    • , Mei Xin
    •  & Q. Richard Lu
  • Article | | open

    Genome-wide association studies (GWAS) have become a key tool to discover genetic markers for complex traits; however, environmental factors that interact with genes are rarely considered. Here, the authors conduct a GWAS of obesity traits, and find that smoking may alter genetic susceptibilities.

    • Anne E. Justice
    • , Thomas W. Winkler
    • , Mary F. Feitosa
    • , Misa Graff
    • , Virginia A. Fisher
    • , Kristin Young
    • , Llilda Barata
    • , Xuan Deng
    • , Jacek Czajkowski
    • , David Hadley
    • , Julius S. Ngwa
    • , Tarunveer S. Ahluwalia
    • , Audrey Y. Chu
    • , Nancy L. Heard-Costa
    • , Elise Lim
    • , Jeremiah Perez
    • , John D. Eicher
    • , Zoltán Kutalik
    • , Luting Xue
    • , Anubha Mahajan
    • , Frida Renström
    • , Joseph Wu
    • , Qibin Qi
    • , Shafqat Ahmad
    • , Tamuno Alfred
    • , Najaf Amin
    • , Lawrence F. Bielak
    • , Amelie Bonnefond
    • , Jennifer Bragg
    • , Gemma Cadby
    • , Martina Chittani
    • , Scott Coggeshall
    • , Tanguy Corre
    • , Nese Direk
    • , Joel Eriksson
    • , Krista Fischer
    • , Mathias Gorski
    • , Marie Neergaard Harder
    • , Momoko Horikoshi
    • , Tao Huang
    • , Jennifer E. Huffman
    • , Anne U. Jackson
    • , Johanne Marie Justesen
    • , Stavroula Kanoni
    • , Leena Kinnunen
    • , Marcus E. Kleber
    • , Pirjo Komulainen
    • , Meena Kumari
    • , Unhee Lim
    • , Jian'an Luan
    • , Leo-Pekka Lyytikäinen
    • , Massimo Mangino
    • , Ani Manichaikul
    • , Jonathan Marten
    • , Rita P. S. Middelberg
    • , Martina Müller-Nurasyid
    • , Pau Navarro
    • , Louis Pérusse
    • , Natalia Pervjakova
    • , Cinzia Sarti
    • , Albert Vernon Smith
    • , Jennifer A. Smith
    • , Alena Stančáková
    • , Rona J. Strawbridge
    • , Heather M. Stringham
    • , Yun Ju Sung
    • , Toshiko Tanaka
    • , Alexander Teumer
    • , Stella Trompet
    • , Sander W. van der Laan
    • , Peter J. van der Most
    • , Jana V. Van Vliet-Ostaptchouk
    • , Sailaja L. Vedantam
    • , Niek Verweij
    • , Jacqueline M. Vink
    • , Veronique Vitart
    • , Ying Wu
    • , Loic Yengo
    • , Weihua Zhang
    • , Jing Hua Zhao
    • , Martina E. Zimmermann
    • , Niha Zubair
    • , Gonçalo R. Abecasis
    • , Linda S. Adair
    • , Saima Afaq
    • , Uzma Afzal
    • , Stephan J. L. Bakker
    • , Traci M. Bartz
    • , John Beilby
    • , Richard N. Bergman
    • , Sven Bergmann
    • , Reiner Biffar
    • , John Blangero
    • , Eric Boerwinkle
    • , Lori L. Bonnycastle
    • , Erwin Bottinger
    • , Daniele Braga
    • , Brendan M. Buckley
    • , Steve Buyske
    • , Harry Campbell
    • , Jaspal S. Kooner
    • , Yii-DerIda Chen
    • , Claes Ohlsson
    • , Morris A. Swertz
    • , Georg Homuth
    • , Barbara Thorand
    • , Lars Lind
    • , Jessica Tyrrell
    • , Annette Peters
    • , Harold Snieder
    • , Bruce M. Psaty
    • , Erik Ingelsson
    • , John-Olov Jansson
    • , M Carola Zillikens
    • , David R. Weir
    • , Mika Kivimaki
    • , Sarah Wild
    • , Graciela E. Delgado
    • , Tamara B. Harris
    • , Maija Hassinen
    • , Ken K. Ong
    • , Dan Mellström
    • , Damiano Baldassarre
    • , Charlotta Pisinger
    • , Ozren Polasek
    • , Albertine J. Oldehinkel
    • , Kirsti Kvaløy
    • , Jaakko Tuomilehto
    • , Igor Rudan
    • , Alan F. Wright
    • , Sandosh Padmanabhan
    • , Barbara McKnight
    • , Nanette R. Lee
    • , Ian Ford
    • , Markku Laakso
    • , Liesbeth Vandenput
    • , Karin Leander
    • , David P. Strachan
    • , Kai Savonen
    • , Winfried März
    • , Marie-Claude Vohl
    • , Catharina A. Hartman
    • , Anna L. Eriksson
    • , Tuomo Rankinen
    • , Ilja M. Nolte
    • , Robert Luben
    • , Stephanie A. Bien
    • , Gitta Lubke
    • , Gudny Eiriksdottir
    • , Joseph Hung
    • , Carsten A. Böger
    • , Timo A. Lakka
    • , Caroline S. Fox
    • , Ulrike Peters
    • , Jessica D. Faul
    • , Eco J. C. de Geus
    • , Hans- Jörgen Grabe
    • , Hester M. den Ruijter
    • , Timothy M. Frayling
    • , Marjo-Riitta Jarvelin
    • , P Eline Slagboom
    • , Elena Tremoli
    • , Heikki A. Koistinen
    • , Min A. Jhun
    • , Rajesh Rawal
    • , Oddgeir L. Holmen
    • , Harald Grallert
    • , Andrew Wong
    • , Gerard Pasterkamp
    • , Konstantin Strauch
    • , Claudia Langenberg
    • , Tim D. Spector
    • , Bamidele O. Tayo
    • , Iris M. Heid
    • , Thorkild I. A. Sørensen
    • , Cristina Menni
    • , Marie Loh
    • , Henrik Vestergaard
    • , Naveed Sattar
    • , James F. Wilson
    • , Penny Gordon-Larsen
    • , Pim van der Harst
    • , Philippe Froguel
    • , Andrew P. Morris
    • , Caroline Hayward
    • , Claudia Schurmann
    • , Anders Hamsten
    • , Reija Männikkö
    • , Narisu Narisu
    • , Stefania Bandinelli
    • , Nicholas J. Wareham
    • , Andre G. Uitterlinden
    • , Diana Kuh
    • , Sara Lupoli
    • , AW (Bill) Musk
    • , Dorret I. Boomsma
    • , David Schlessinger
    • , Saskia Haitjema
    • , Jan A. Staessen
    • , Kent D. Taylor
    • , Nicola Glorioso
    • , Treva Rice
    • , Peter S. Chines
    • , Francis S. Collins
    • , David J. Hunter
    • , Paul W. Franks
    • , Torben Hansen
    • , Matthias Nauck
    • , Laura J. Rasmussen-Torvik
    • , D. C. Rao
    • , Cornelia M. van Duijn
    • , George Dedoussis
    • , John C. Chambers
    • , Ruth J. F. Loos
    • , L Adrienne Cupples
    • , Niels Grarup
    • , Blair H. Smith
    • , Joanne E. Curran
    • , Grant W. Montgomery
    • , Tanja B. Grammer
    • , Dorothee Thuillier
    • , Melanie Waldenberger
    • , Richard S. Cooper
    • , J Wouter Jukema
    • , Lynne J. Hocking
    • , Beverley Balkau
    • , Gérard Waeber
    • , Tõnu Esko
    • , Mark A. Sarzynski
    • , Anton J. M. de Craen
    • , Bengt Sennblad
    • , Luigi Ferrucci
    • , Peter Vollenweider
    • , Inês Barroso
    • , Gert J. de Borst
    • , Jouke Jan Hottenga
    • , Robert A. Scott
    • , Lenore J. Launer
    • , Göran Hallmans
    • , Loic Le Marchand
    • , Sharon L. R. Kardia
    • , Marit E. Jørgensen
    • , Bernhard K. Krämer
    • , Jonathan Marchini
    • , Christopher A. Haiman
    • , Alan L. James
    • , Marten A. Siemelink
    • , Lyle J. Palmer
    • , Kari E. North
    • , Charles Kooperberg
    • , Bruna Gigante
    • , Nicholas D. Hastie
    • , Mette Hollensted
    • , Dena Hernandez
    • , Lynda M. Rose
    • , Tuomas O. Kilpeläinen
    • , Ingrid B. Borecki
    • , Rainer Rauramaa
    • , Lu Qi
    • , Olli T. Raitakari
    • , Panagiotis Deloukas
    • , David J. Porteous
    • , R. G. J. Westendorp
    • , Wei Zhao
    • , Joel N. Hirschhorn
    • , Magnus Karlsson
    • , Terho Lehtimäki
    • , Henry Völzke
    • , Andrew D. Johnson
    • , David J. Stott
    • , Andrew C. Heath
    • , Allan Linneberg
    • , Markus Juonala
    • , John B. Whitfield
    • , Bruce H. R. Wolffenbuttel
    • , Terrence Forrester
    • , Ching-Ti Liu
    • , Karl Gertow
    • , Jian Gong
    • , Claude Bouchard
    • , Pedro Marques-Vidal
    • , Amy J. Swift
    • , Vilmundur Gudnason
    • , Paul M. Ridker
    • , Kristian Hveem
    • , Lucia Hindorff
    • , Colin A. McKenzie
    • , Anja Ludolph-Donislawski
    • , Salome Scholtens
    • , Patricia A. Peyser
    • , Ulf de Faire
    • , Mark I. McCarthy
    • , Jie Huang
    • , Nicholas G. Martin
    • , Mika Kähönen
    • , Henning Tiemeier
    • , Oluf Pedersen
    • , Mattias Lorentzon
    • , Serena Sanna
    • , Matthias Olden
    • , Judith M. Vonk
    • , Stephane Lobbens
    • , Andres Metspalu
    • , Cecilia M. Lindgren
    • , Karen L. Mohlke
    • , Nina Hutri-Kähönen
    • , Francesco Cucca
    • , Pamela A. F. Madden
    • , Daniel I. Chasman
    • , Günther Silbernagel
    • , Gonneke Willemsen
    • , Marcel Bruinenberg
    • , Daniele Cusi
    • , Ivana Kolcic
    • , Michael Boehnke
    • , Johanna Kuusisto
    •  & Genovefa Kolovou
  • Article | | open

    Cortical thickness has high heritability estimates and is known to be influenced by genetic factors. Here, Freytag and colleagues show that DNA methylation patterns of peripheral blood monocytes are also correlated with cortical thickness and memory performance in human.

    • Virginie Freytag
    • , Tania Carrillo-Roa
    • , Annette Milnik
    • , Philipp G. Sämann
    • , Vanja Vukojevic
    • , David Coynel
    • , Philippe Demougin
    • , Tobias Egli
    • , Leo Gschwind
    • , Frank Jessen
    • , Eva Loos
    • , Wolfgang Maier
    • , Steffi G. Riedel-Heller
    • , Martin Scherer
    • , Christian Vogler
    • , Michael Wagner
    • , Elisabeth B. Binder
    • , Dominique J. -F. de Quervain
    •  & Andreas Papassotiropoulos
  • Article | | open

    In lithium-ion batteries the interactions between the electrode and electrolyte represent a complex but critical process. Here the authors reveal the dynamic behaviour of interphases driven by conductive carbon through chemical and imaging analyses of a model transition-metal oxide cathode material.

    • Wangda Li
    • , Andrei Dolocan
    • , Pilgun Oh
    • , Hugo Celio
    • , Suhyeon Park
    • , Jaephil Cho
    •  & Arumugam Manthiram